Xiidra (Lifitegrast) is a prescription eye drop used to treat the signs and symptoms of dry eye disease. It works by targeting inflammation on the surface of the eye, which is believed to be a major cause of dry eye symptoms. Xiidra is typically prescribed as a long-term treatment, with one drop applied to each eye twice daily.
Without insurance, Xiidra (Lifitegrast) can be expensive, with U.S. retail pharmacy prices ranging from $794 to over $869 per 30-day supply.
Key Takeaways
Online Pharmacies Offer Significant Savings: CIPA-certified international pharmacies like DrugMart list Xiidra (Lifitegrast) at $462.48 for a 60-vial pack—about 45% less than the average U.S. retail price. Purchase from DrugMart.com
U.S. Pharmacies Charge $794–$869 Monthly Without Insurance: U.S. retailers including Walgreens, Walmart, and CVS list Xiidra (Lifitegrast) at retail prices approaching $800–$870 for a 30-day supply.
Xiidra Is Covered by Medicare and Private Insurance: Coverage varies by plan. Xiidra is typically on Tier 3 or 4 of Medicare Part D plans and may require prior authorization. Out-of-pocket costs depend on the formulary tier, deductible, and coinsurance.
Cheapest Online Pharmacies for Xiidra (Lifitegrast)
Cheapest online pharmacies selling Xiidra (Lifitegrast):
Pharmacy | Prescription Required | Price (60 Vials) | Dosage | Website |
DrugMart | Yes | $462.48 | 5% | |
Planet Drugs Direct | Yes | $492.99 | 5% | |
Amazon Pharmacy | Yes | $733.98 | 5% | |
HealthWarehouse | Yes | $785.00 | 5% |
Prices as of July 1, 2025. May vary by quantity, location, and shipping origin.
U.S. Retail Prices for Xiidra (Lifitegrast)
U.S. retail pharmacy prices for Xiidra (Lifitegrast):
Pharmacy | Retail Price (30-Day Supply) |
Meijer Pharmacy | $869.07 |
Aurora Pharmacy | $869.07 |
Mariano’s | $869.07 |
Capsule Pharmacy | $869.07 |
Jewel-Osco | $794.69 |
CVS / Target (CVS) | $852.99 |
Walgreens / Walgreens Specialty | $864.72 |
Walmart / Neighborhood Market | $853.46 |
Costco | $869.07 |
Prices as of July 1, 2025. Actual costs may vary depending on insurance status and location.
How to Save on Xiidra (Lifitegrast)
Here’s how to save on Xiidra (Lifitegrast):
1. Use Medicare Part D or Commercial Insurance
Xiidra is covered by most Medicare Part D plans, though it often falls under Tier 3 or Tier 4 and may require prior authorization. The copay or coinsurance can vary widely depending on plan design and coverage phase.
Tip: Use the Medicare Plan Finder tool or your insurance member portal to view expected out-of-pocket costs.
2. Xiidra Copay and Cash Discount Program
Xiidra My Savings Program (by Bausch + Lomb)
Eligible commercially insured patients may pay as little as $0 per fill
For uninsured or non-covered patients, fixed cash prices:
$250 (30-day), $500 (60-day), or $750 (90-day)
Covers up to 12 fills per year
Not valid for patients with Medicare, Medicaid, or government coverage
Activate your savings card online at xiidra.blsavingscard.com. Or call 1-877-494-4372 for assistance
3. CIPA-Certified Online Pharmacies
Ordering from licensed international pharmacies can reduce the monthly cost of Xiidra (Lifitegrast) by up to 50%. These pharmacies ship from Canada or other regulated countries and require a valid prescription.
Ready to order? Purchase from DrugMart.com
Common Questions About Xiidra (Lifitegrast)
Common questions and answers about Xiidra (Lifitegrast):
1. Is Xiidra (Lifitegrast) covered by Medicare?
Yes. Xiidra is typically covered under Medicare Part D plans and some Medicare Advantage plans with prescription drug coverage. However, it is usually placed on mid-to-high formulary tiers and may require prior authorization. Costs can vary by deductible stage and plan.
2. Are there savings programs for Xiidra (Lifitegrast)?
Yes. The Xiidra My Savings Program helps eligible commercially insured patients pay as little as $0 per fill. Patients without insurance can receive discounts on 30-, 60-, or 90-day supplies for fixed prices. This program is not valid for Medicare or Medicaid beneficiaries.
3. How much will Xiidra (Lifitegrast) cost per year?
Here’s how much Xiidra (Lifitegrast) could cost per year if used for long-term treatment of dry-eye disease:
Purchase Method | Monthly Estimate | Annual Estimate |
U.S. Retail Pharmacies | $794 – $869 | $9,528 – $10,428 |
CIPA-certified Online Pharmacy (DrugMart) | ~$462.48 | ~$5,550 |
Medicare Part D (with coverage) | $0 – $150+ | $0 – $1,800+ |
Xiidra My Savings (cash pay) | $250 (monthly rate) | $3,000 |
4. Why is Xiidra (Lifitegrast) so expensive?
Several factors contribute to the high cost of Xiidra (Lifitegrast):
Brand-name exclusivity: Xiidra (Lifitegrast) is a patented brand-name drug with no generic equivalent available. Without generic competition, the manufacturer has exclusive pricing power.
Research and development (R&D) costs: Developing new medications requires extensive research, clinical trials, and regulatory approvals. These investments are built into the price of brand-name drugs like Xiidra.
No generic alternatives: The absence of a lower-cost, generic version of Xiidra (Lifitegrast) means there is no competitive downward pressure on pricing.
Insurance variability: While some private insurance plans cover Xiidra (Lifitegrast), Medicare and Medicaid coverage can vary, and out-of-pocket costs are often higher without prior authorization or formulary placement.
High cash price: Without insurance or discounts, a 30-day supply of Xiidra (Lifitegrast) can cost between $748 and $869, with annual costs exceeding $9,000 at retail price. However, discounts and manufacturer savings programs may significantly reduce that amount for eligible patients.
Purchase Your Over-the-Counter and Prescription Drugs From https://Drugmart.com You can rely on https://Drugmart.com for over-the-counter and prescription drugs at a discount. We're a leading referral service for patients who want to order medications from Canada online and other international partners, offering unparalleled customer service. If you have any questions, be sure to contact our outstanding customer service representatives for the answers you need.
Sources
Bausch & Lomb Incorporated. Xiidra Cost & Savings Programs. Accessed July 2, 2025. https://www.xiidra.com/xiidra-cost/
Bausch & Lomb Incorporated. Xiidra (lifitegrast ophthalmic solution) Prescribing Information [PDF]. Accessed July 2, 2025. https://pi.bausch.com/globalassets/pdf/packageinserts/pharma/xiidra-prescribing-information.pdf
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