BRUKINSA® (Zanubrutinib) is an oral prescription medication used to treat certain B-cell malignancies, including mantle cell lymphoma (MCL), Waldenström's macroglobulinemia (WM), chronic lymphocytic leukemia (CLL), and small lymphocytic lymphoma (SLL). It works as a Bruton’s tyrosine kinase (BTK) inhibitor, blocking signals that help cancer cells survive and multiply. BRUKINSA® is typically taken twice daily as part of a long-term cancer treatment plan.
Without insurance, BRUKINSA® (Zanubrutinib) can be costly, with U.S. retail pharmacy prices averaging about $3,906–$3,933 for a 30-day supply of 80 mg capsules.
Key Takeaways
Online Pharmacies Offer Substantial Savings: CIPA-certified international pharmacies like DrugMart list BRUKINSA® (Zanubrutinib) at $40,695.38 for a 360-capsule supply—saving roughly 65% or more compared to many U.S. retail prices.
U.S. Pharmacies Charge Around $3,906–$3,933 Monthly Without Insurance: Prices per 80 mg capsule average $130–$131 in the U.S.
BRUKINSA® Is Covered by Medicare and Private Insurance: Coverage is typically under Tier 5 (specialty tier) and may require prior authorization.
Cheapest Online Pharmacies for BRUKINSA® (Zanubrutinib)
Pharmacy | Prescription Required | Price | Dosage | Supply | Price per Capsule | Website |
DrugMart | Yes | $40,695.38 | 80 mg | 360 capsules | $113.04 | |
Planet Drugs Direct | Yes | $44,766.99 | 80 mg | 360 capsules | $124.35 | |
Blink Health | Yes | $3,939.53 | 80 mg | 30 capsules | $131.32 |
Prices as of August 15 2025. May vary by quantity, shipping origin, and dosage strength.
U.S. Retail Prices for BRUKINSA® (Zanubrutinib)
Pharmacy | Retail Price (30-Day Supply) |
CVS Pharmacy | $3,906.52 |
CVS Inside Target | $3,906.52 |
Walgreens | $3,933.48 |
Prices as of August 15 2025. Actual costs may vary by location and insurance status.
How to Save on BRUKINSA® (Zanubrutinib)
1. Use Medicare Part D or Commercial Insurance
BRUKINSA® is covered by most Medicare Part D and commercial insurance plans but is generally placed on a high-cost specialty tier. This means coinsurance is often calculated as a percentage of the drug’s price unless the 2025 Medicare $2,000 out-of-pocket cap applies.
Tip: Use your Medicare Plan Finder tool or insurer’s drug cost estimator to get an accurate monthly cost.
2. Manufacturer Co-pay and Patient Assistance Programs
BeiGene Patient Assistance Program
For commercially insured patients: Eligible patients may pay as little as $0 per month
Offers co-pay support and assistance navigating insurance
Phone: 1-833-BEIGENE (1-833-234-4363)
Website: beigene.com/patients
Foundations and Nonprofit Support
Organizations like the PAN Foundation and Leukemia & Lymphoma Society may offer additional copay or premium assistance.
3. CIPA-Certified Online Pharmacies
Ordering from licensed international pharmacies can lower costs by over 60%. All orders require a valid prescription and ship from regulated facilities in Australia or Canada.
Common Questions About BRUKINSA® (Zanubrutinib)
1. Is BRUKINSA® covered by Medicare?
Yes. Most Medicare Part D and Advantage plans with drug coverage list BRUKINSA® (Zanubrutinib) in their formularies, usually on a specialty tier with prior authorization requirements.
2. Can I use manufacturer co-pay assistance with Medicare?
No. Manufacturer co-pay programs generally exclude Medicare and Medicaid beneficiaries. However, nonprofit patient assistance programs may help.
3. How much will BRUKINSA® (Zanubrutinib) cost per year?
Purchase Method | Monthly Estimate | Annual Estimate |
U.S. Retail Pharmacies | $3,906 – $3,933 | $46,872 – $47,196 |
CIPA Online Pharmacy (DrugMart) | ~$3,391* | ~$40,695* |
Medicare Part D (2025 cap) | Max $2,000/year | $2,000 |
BeiGene Co-pay Program | As low as $0 | Varies (max benefit applies) |
*Based on prorated cost of a 360-capsule supply from DrugMart.
Rely on DrugMart.com to Buy Online Prescription Brukinsa
We are a reliable prescription referral service, providing significant advantages when you order your prescriptions online. Our affiliated pharmacies and government-approved dispensaries strive to offer an unmatched experience compared to other online referral services. We offer:
Low prices
Quick turnaround times
Generic and brand-name medications
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Sources
BeiGene USA. BRUKINSA® Prescribing Information [PDF]. Accessed August 15, 2025.
Centers for Medicare & Medicaid Services. Medicare Part D Drug Spending Dashboard. Accessed August 15, 2025.
DrugMart.com – BRUKINSA Price Page. Accessed August 15, 2025.
PlanetDrugsDirect.com – BRUKINSA Price Page. Accessed August 15, 2025.
BlinkHealth.com – BRUKINSA Price Page. Accessed August 15, 2025.
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