Vyndamax (Tafamidis) is a prescription oral medication used to treat transthyretin amyloid cardiomyopathy (ATTR-CM), a progressive and life-threatening condition caused by deposits of misfolded transthyretin proteins in the heart. It works by stabilizing the transthyretin protein to prevent these deposits from forming.
Without insurance, Vyndamax (Tafamidis) can be prohibitively expensive, with U.S. retail pharmacy prices ranging from $23,334 to over $24,500 per month.
Key Takeaways
Online Pharmacies Offer Significant Savings: International, CIPA-certified pharmacies like DrugMart list Vyndamax (Tafamidis) at $27,457.43 for a 3-month supply—about $9,152 per month—saving 60% or more over many U.S. pharmacy prices. Purchase from DrugMart.com
U.S. Pharmacies Charge $23,334–$24,528 Monthly Without Insurance: U.S. retailers such as Walgreens and Kroger list Vyndamax (Tafamidis) at over $23,000 per 30-day supply.
Vyndamax Is Covered by Medicare and Private Insurance: Coverage often requires prior authorization and may include substantial coinsurance or tiered copays, especially under specialty tiers.
Cheapest Online Pharmacies for Vyndamax (Tafamidis)
Online pharmacies offering Vyndamax (Tafamidis):
Pharmacy | Prescription Required | Price (30 Capsules) | Dosage | Website |
DrugMart | Yes | $9,152.48 | 61mg | |
Planet Drugs Direct | Yes | $9,467.33 | 61mg | |
Blink Health | Yes | $23,327.47 | 61mg |
Prices as of July 1, 2025. May vary by quantity, shipping, and country of origin.
U.S. Retail Prices for Vyndamax (Tafamidis)
U.S. retail prices for Vyndamax (Tafamidis):
Pharmacy | Retail Price (30-day Supply) |
Kroger Pharmacy | $23,334.41 |
Walgreens | $24,527.86 |
Prices as of July 1, 2025. May vary by location and insurance status.
How to Save on Vyndamax (Tafamidis)
Here’s how to save on Vyndamax (Tafamidis):
1. Use Medicare Part D or Commercial Insurance
Vyndamax (Tafamidis) is covered by most Medicare Part D plans and commercial insurers. It often appears on high-cost specialty tiers (e.g., Tier 5), and many plans require prior authorization.
Tip: Use the Medicare Plan Finder or your insurance portal to estimate true monthly out-of-pocket costs.
2. Vyndamax Co-pay Assistance and Patient Support Programs
Here are the various Vyndamax (Tafamidis) co-pay and patient support programs available to patients:
Pfizer Co-Pay Savings Program
For commercially insured patients
Pay as little as $0 per month
Annual savings limit up to $60,000
Not valid for federal or state healthcare program beneficiaries
Phone: 888-222-8475 | Visit Website
Pfizer Patient Assistance Program (RxPathways)
For uninsured or underinsured patients
Offers free medication to eligible individuals
Must reside in the U.S. or U.S. territory
Phone: 866-706-2400 | Visit Website
VyndaLink Patient Support Program
Offers copay, reimbursement, and education support
For eligible patients at or below 300% of the federal poverty level (FPL)
FDA-approved diagnosis required
Phone: 888-222-8475 | Visit Website
PAN Foundation & HealthWell Foundation
Nonprofit financial aid for insured patients
Assistance with copays, deductibles, and premiums
PAN: 866-316-7263 | Visit Website
HealthWell: 800-675-8416 | Visit Website
3. CIPA-Certified Online Pharmacies
Purchase from licensed Canadian and international pharmacies to save over 60 percent.
A valid prescription is required.
Medications ship from Canada, the UK, or Australia.
Ready to order? Purchase from DrugMart.com
Common Questions About Vyndamax (Tafamidis)
Common questions and answers about Vyndamax (Tafamidis):
1. Is Vyndamax (Tafamidis) covered by Medicare?
Yes. Vyndamax is covered under most Medicare Part D and Advantage plans with drug coverage. It is typically placed on a specialty tier and often requires prior authorization. Costs vary depending on the coverage phase (deductible, initial coverage, coverage gap, catastrophic).
2. Can I use the Pfizer Co-pay card with Medicare?
No. The Pfizer Co-pay Savings Program is only available to patients with commercial insurance. Medicare, Medicaid, and other government health plans are excluded.
3. How much will Vyndamax (Tafamidis) cost per year?
Here’s how the annual cost of Vyndamax compares by purchase method:
Purchase Method | Monthly Estimate | Annual Estimate |
U.S. Retail Pharmacies | $23,334 – $24,528 | $280,000 – $294,000 |
CIPA Online Pharmacy (DrugMart) | ~$9,152 (prorated 3-month) | ~$109,824 |
Medicare Part D (w/ Extra Help) | $0 – $3,000+ | $0 – $15,000+ |
Find Affordable Brand-Name and Generic Drugs at Drugmart.com At Drugmart.com, we pride ourselves on our affordability, exceptional quality and ease of use when our patients shop for both brand-name and generic drugs. We work closely with the world's most reputable pharmacies to provide high-quality medications from Canada and other tier 1 international sources at unmatched prices, so you can get the treatment you need without worrying about affordability.
Sources
Pfizer Inc. Vyndamax Patient Brochure [PDF]. Published May 2024. Accessed July 6, 2025. https://www.vyndamax.com/sites/default/files/2024-05/PP-VDM-USA-1740%20VYNDAMAX%20Patient%20DIGITAL%20Brochure.pdf
Pfizer Inc. Vyndalink Access Brochure for Healthcare Professionals [PDF]. Accessed July 6, 2025. https://www.vyndalink.com/files/HCP-Access-Brochure_new.pdf
Pfizer Inc. Vyndamax Post-Rx Patient Roadmap [PDF]. Published December 2023. Accessed July 6, 2025. https://www.vyndamax.com/sites/default/files/2023-12/1907459_L33_VYN_PostRxMap_Patient_FC_Digital_INTERACTIVE.pdf
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