Linzess (Linaclotide) is a once-daily oral medication used to treat irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC). It works locally in the intestines by increasing fluid secretion and accelerating transit time, relieving abdominal pain and discomfort.
Linzess (Linaclotide) can be expensive without insurance, with U.S. pharmacy retailer prices ranging anywhere from $630 to $700 per month for patients.
Key Takeaways
CIPA-Certified Online Pharmacies Offer Major Savings: Trusted pharmacies like DrugMart and Planet Drugs Direct list Linzess as low as $229.34, a discount of over 65% compared to U.S. prices. Purchase from DrugMart.com.
U.S. Pharmacies Charge $630–$698 Without Insurance: Retail prices at CVS, Walgreens, Walmart, and others range from $630 to $698 for a 30-capsule supply.
Linzess Is Covered by Most Medicare Part D Plans: Linzess is typically included on Tier 3 of Medicare formularies, but coverage details, copays, and deductibles vary by plan.
Manufacturer Savings for Privately Insured Patients Only: The Linzess Savings Program allows eligible patients with private insurance to pay as little as $30, but it is not valid for Medicare beneficiaries.
Cheapest Online Pharmacies for Linzess (Linaclotide)
Cheapest online pharmacies to purchase Linzess (Linaclotide):
Pharmacy | Prescription Required | Price | Dosage | Website |
DrugMart | Yes | $229.34 | 72mcg | |
Planet Drugs Direct | Yes | $244.99 | 72mcg | |
Amazon Pharmacy | Yes | $509.00 | 72mcg |
Prices as of June 2, 2025. May vary by quantity, shipping, and country of origin.
U.S. Retail Prices for Linzess (Linaclotide)
Here is what most U.S. retail pharmacies charge for Linzess (Linaclotide):
Pharmacy | Retail Price |
Meijer Pharmacy | $710.80 |
Aurora Pharmacy | $797.44 |
Mariano's | $678.13 |
Capsule Pharmacy | $677.01 |
Jewel-Osco | $630.90 |
Walgreens | $660.52 |
Walgreens Specialty | $660.99 |
Walmart | $681.94 |
Walmart Neighborhood Market | $681.58 |
CVS Pharmacy | $683.18 |
Target (CVS) | $683.07 |
Costco | $698.32 |
Prices shown are for a 30-day supply (72mcg capsules). Local pricing may vary.
How to Save on Linzess (Linaclotide)
Here’s how to save on Linzess (Linaclotide):
1. Use Medicare Part D or Medicare Advantage
Linzess is widely covered under most plans but is typically placed on Tier 3.
Your costs depend on the plan’s tier, deductible, and which phase you're in (initial, coverage gap, or catastrophic).
Some plans require prior authorization.
Tip: Review your plan’s formulary or contact your provider to confirm details.
2. Manufacturer Savings Programs
Eligible patients with private/commercial insurance may qualify for the Linzess Savings Program:
Pay as little as $30 per 30-, 60-, or 90-day fill
Cannot be used with Medicare, Medicaid, or other government-funded programs
Requires enrollment through Linzess.com
Learn more about the Linzess Savings Program through AbbVie.
3. CIPA-Certified Online Pharmacies
International online pharmacies can cut costs by up to 75%, with prices starting under $230. These pharmacies:
Require a valid prescription
Ship from licensed pharmacies abroad
Are certified by the Canadian International Pharmacy Association (CIPA)
Ready to save up to 75% on your prescription? Purchase from DrugMart.com
Common Questions About Linzess (Linaclotide)
Common questions and answers about Linzess (Linaclotide):
1. Is Linzess covered by Medicare?
Yes. Most Medicare Part D and Advantage plans cover Linzess, but costs depend on your plan tier and phase of coverage.
2. Can I use the Linzess savings card with Medicare?
No. The Linzess savings program is only for patients with commercial insurance. It cannot be used with Medicare, Medicaid, or other government-funded programs.
3. How much will Linzess cost per year?
Here’s how much Linzess (Linaclotide) could cost per year based on the method that you choose to purchase your prescription:
Method | Monthly Estimate | Annual Estimate |
U.S. Retail Pharmacies (Uninsured) | $630 – $698 | $7,560 – $8,376 |
CIPA International Pharmacy | $229.34 lowest price through DrugMart.com | $2,752.08 |
Medicare Part D | $0 – $100+ | $600 – $1,200 |
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Sources
Linzess®. (n.d.). Linzess Savings Program. Retrieved June 2, 2025, from https://www.linzess.com/starting-linzess/linzess-savings-program
U.S. Food and Drug Administration. (2017). Linzess (linaclotide) [Labeling] (NDAs 202811/S‑013). Retrieved June 2, 2025, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/202811s013lbl.pdf
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