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Cymbalta (Duloxetine Hydrochloride) Price – Save Over 70% (Guide)

A man sitting on a sofa at home is sad, disappointed and upset.

Cymbalta (Duloxetine Hydrochloride) is an oral prescription medication used to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), diabetic peripheral neuropathic pain, fibromyalgia, and chronic musculoskeletal pain. Internationally, it is also marketed under the name Yentreve, particularly for stress urinary incontinence in women. It is typically taken once or twice daily, with dosing dependent on the condition being treated. Without insurance, 

Cymbalta can be significantly less expensive when purchased through CIPA-certified online pharmacies compared to U.S. retail prices.

Key Takeaways

  • Online Pharmacies Offer Significant Savings: International versions of Cymbalta (Yentreve) are available from $2.70 per capsule, saving more than 70% compared to some U.S. retail prices.

  • U.S. Pharmacies Charge Higher Monthly Rates: Amazon Pharmacy lists Cymbalta at over $8.52 per capsule for 20 mg strength.

  • Generic Duloxetine is widely available: In the U.S., duloxetine is available at lower prices through retail and discount pharmacies.

Cheapest Online Pharmacies for Cymbalta (Duloxetine Hydrochloride / Yentreve)

Pharmacy

Prescription Required

Price

Dosage

Supply

Price per Capsule

Website

DrugMart

Yes

$227.11

20 mg

84 capsules

$2.70

Visit

Planet Drugs Direct

Yes

$242.99

20 mg

84 capsules

$2.89

Visit

Amazon Pharmacy

Yes

$255.70

20 mg

30 capsules

$8.52

Visit

U.S. Retail Prices for Cymbalta (Duloxetine Hydrochloride)

Pharmacy

Retail Price (30-Day Supply)

Amazon Pharmacy

$255.70

Major U.S. chains (generic duloxetine)

$4 – $30 with discount

How to Save on Cymbalta (Duloxetine Hydrochloride)

1. Use Medicare Part D or Commercial Insurance

Cymbalta and generic duloxetine are covered by most Medicare Part D and commercial insurance plans, typically on lower tiers for the generic version. Brand-name Cymbalta may be placed on higher tiers, leading to higher copays.

2. Choose Generic Duloxetine

Generic duloxetine is widely available in the U.S., often for under $10 per month with discount cards or insurance.

3. CIPA-Certified Online Pharmacies

International versions such as Yentreve can be purchased from licensed pharmacies in the UK or EU for a fraction of U.S. retail costs.

Common Questions About Cymbalta (Duloxetine Hydrochloride)

1. Is Cymbalta covered by Medicare?

Yes. Both brand-name Cymbalta and generic duloxetine are typically covered under Medicare Part D plans, though the generic is usually on a much lower-cost tier.

2. Is there a generic for Cymbalta?

Yes. Duloxetine Hydrochloride is the generic form and is widely available in the U.S. and abroad at substantially lower prices.

3. How much will Cymbalta cost per year?

Purchase Method

Monthly Estimate

Annual Estimate

CIPA Online Pharmacy (DrugMart)

~$80.57

~$966.84

CIPA Online Pharmacy (Planet Drugs Direct)

~$84.91

~$1,018.92

Amazon Pharmacy (brand)

~$255.70

~$3,068.40

U.S. generic (discount)

$4 – $30

$48 – $360

Rely on DrugMart.com to Buy Online Prescription Cymbalta

Our prescription referral service gives you access to important benefits when you order online. Every pharmacy and government-approved dispensary in our network is committed to providing the highest quality experience among online prescription referral services. We offer:

  • Low prices

  • Quick turnaround times

  • Generic and brand-name medications

  • Unparalleled customer service


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The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.