Xenical (Orlistat) is a prescription medication used to support weight loss in adults who are overweight or obese. It belongs to a drug class called lipase inhibitors, which work by preventing the body from absorbing about 25% of the fat you eat. Instead, the undigested fat is eliminated through bowel movements. Xenical contains orlistat 120 mg as the active ingredient and is intended for use alongside a reduced-calorie, low-fat diet.
Unlike stimulant-based weight loss medications, Xenical works directly in the digestive tract and has minimal systemic absorption. It is commonly prescribed for long-term weight management, particularly in individuals with risk factors like high blood pressure, type 2 diabetes, or high cholesterol.
Xenical (orlistat) is taken three times daily with each main meal containing fat. When combined with a diet and exercise program, Xenical can help increase the likelihood of achieving and maintaining weight loss.
Key Takeaways
Availability: Xenical (Orlistat 120mg) is available by prescription from licensed pharmacies and online platforms. The most affordable option is DrugMart at $39.33 for 30 capsules. To purchase from DrugMart, go right here.
How It Works: Xenical (Orlistat) inhibits gastrointestinal enzymes called lipases, blocking fat absorption and promoting elimination of dietary fats through the stool.
Common Side Effects: These include oily stools, gas with discharge, increased bowel movements, and abdominal discomfort, especially when consuming high-fat meals.
4 Places to Buy Xenical (Orlistat) Online
Xenical (Orlistat) is available through certified online pharmacies and health platforms. Prices below have been adjusted to reflect the cost of 30 capsules of the 120 mg dosage.
Provider | Adjusted Price (30 Capsules) | Prescription Required | Dosage | Link |
DrugMart | $39.33 | Yes | 120 mg | |
PlanetDrugsDirect | $42.00 | Yes | 120 mg | |
Amazon Pharmacy | $147.52 | Yes | 120 mg | |
Marley Drug | $276.33 | Yes | 120 mg |
Prices reflect a 30-capsule adjusted comparison based on original bulk quantities. Data updated as of April 2025. Please note that prices may change based on your milligram requirements or the current date.
Where to Buy Xenical (Orlistat) Online
Here are the best places to purchase Xenical (Orlistat) online:
1. DrugMart
Adjusted Price (30 capsules): $39.33
Prescription Required: Yes
Best For: Cheapest option for brand-name Xenical (Orlistat) from a CIPA-certified online pharmacy.
2. PlanetDrugsDirect
Adjusted Price (30 capsules): $42.00
Prescription Required: Yes
Best For: Trusted international pharmacy with bulk discounts. Trusted CIPA-certified online pharmacy.
3. Amazon Pharmacy
Price: $147.52 for 30 capsules
Prescription Required: Yes
Best For: U.S.-based shoppers preferring fast fulfillment and Prime delivery
4. Marley Drug
Price: $276.33 for 30 capsules
Prescription Required: Yes
Best For: Direct pharmacy with bundled services and refill programs
What is Xenical (Orlistat)?
Xenical (Orlistat) is a weight loss medication that helps prevent the absorption of dietary fat. Unlike appetite suppressants, Xenical works locally in your digestive system by blocking the enzymes (lipases) that break down fat. This causes about one-quarter of the fat you eat to be eliminated undigested. It's FDA-approved for use in adults with a BMI ≥30, or ≥27 with comorbidities such as high blood pressure or type 2 diabetes.
Warnings
Do not take Xenical (Orlistat) if you:
Have chronic malabsorption syndrome
Have cholestasis (a liver/bile condition)
Are pregnant
Are allergic to orlistat or any of its ingredients
Before Taking Xenical (Orlistat)
Let your doctor know if you:
Have kidney stones or kidney disease
Are taking cyclosporine, warfarin, or thyroid medications
Have a history of eating disorders
How to Take Xenical (Orlistat)
Take one 120 mg capsule three times per day with meals that contain fat.
Skip a dose if the meal is fat-free.
Use in conjunction with a reduced-calorie, low-fat diet and regular exercise.
Take a multivitamin supplement at least 2 hours before or after dosing.
Missed Dose or Overdose
Missed Dose: Skip it and continue with the next meal. Do not double the dose.
Overdose: Call Poison Help at 1-800-222-1222. Overdose may cause gastrointestinal symptoms.
Xenical (Orlistat) Side Effects
Here are common and serious side effects of Xenical (Orlistat):
Common Side Effects:
Oily or fatty stools
Flatulence with discharge
Frequent or urgent bowel movements
Abdominal pain or discomfort
Incontinence
Serious Side Effects (Contact your doctor):
Severe liver injury (rare)
Kidney stones
Allergic reactions
Rectal bleeding
Count on https://Drugmart.com When You Need to Import Prescription Drugs Through Canada When you work with https://Drugmart.com, ordering medicine through Canada is easy, safe and cost-effective. You can rely on our reputable network of pharmacies to deliver the authentic drugs you need. If you're ready to import prescription drugs through Canada and our other verified international pharmacies, you can start today by browsing our available medications.
Sources
U.S. Food and Drug Administration. Xenical (orlistat) capsules, for oral use: Prescribing information. Silver Spring, MD: U.S. Dept. of Health and Human Services; 2022. Accessed May 7, 2025. https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/020766s038lbl.pdf
Related Articles
How Long Do Semaglutide Side Effects Last
Semaglutide is the active ingredient and drug in common Type-2 diabetes medications such as Wegovy and Ozempic. Both of these medications have common short-term side effects as well as long-term side effects....
CIPA: How Online Canadian Pharmacies Save You Money
The Canadian International Pharmacy Association (CIPA) was formed in 2002. Their job is to work with regulators, pharmacists, physicians, consumer special interest groups, government members and...
Tirzepatide vs Semaglutide: Effectiveness and Similarities
Tirzepatide (Zepbound or Mounjaro) and semaglutide (Ozempic) are often referred to as “weightloss medications” that help those suffering from chronic obesity to lose weight. Both...
