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(Bupropion Hydrochloride)
Prescription required. Can not be split. Product of New Zealand. Shipped from New Zealand.
Zyban (bupropion) is a prescription medication used primarily for smoking cessation by reducing nicotine cravings and withdrawal symptoms. It helps individuals gradually quit smoking by altering neurotransmitter activity in the brain. Unlike nicotine replacement therapies, Zyban does not contain nicotine but instead influences dopamine and norepinephrine levels to reduce dependence on cigarettes.
While primarily used for smoking cessation, bupropion is also prescribed under the brand name Wellbutrin for:
Major Depressive Disorder (MDD)
Seasonal affective disorder (SAD)
To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more
Zyban is prescribed to individuals who wish to quit smoking but struggle with withdrawal symptoms, such as irritability and strong urges to smoke. By modifying brain chemistry, Zyban can:
Reduce the severity of nicotine cravings.
Decrease withdrawal symptoms that make quitting difficult.
Improve the likelihood of long-term smoking cessation.
Physicians may also suggest combining Zyban with nicotine replacement therapies (NRT) like patches or gum for additional support.
Zyban should be taken as prescribed by a healthcare provider to ensure effectiveness and minimize side effects.
Take exactly as directed by your physician. Do not take more than prescribed, as excessive doses can increase the risk of seizures.
Initial Dose: 150 mg orally once daily for three days.
Maintenance Dose: May be increased to 150 mg twice daily, with at least 8 hours between doses.
In some instances, smoking may continue for the first week of treatment. However, a quit date should be set for the second week of Zyban use.
If smoking cessation is not achieved within 7 weeks, your physician may re-evaluate the treatment plan.
Zyban can be taken with or without food to minimize stomach discomfort.
Do not crush, chew, or break tablets; this can interfere with the medication's controlled release.
Do not stop Zyban suddenly unless directed by a doctor. Although Zyban is not habit-forming, abrupt discontinuation can lead to withdrawal symptoms due to sudden shifts in neurotransmitter levels.
If you miss a dose, skip it if your next scheduled dose is soon.
Do not take extra medication to make up for a missed dose.
Overdosing on Zyban can be fatal and may cause severe seizures, hallucinations, irregular heartbeat, shallow breathing, or loss of consciousness.
If an overdose is suspected, seek emergency medical attention immediately or call Poison Control at 1-800-222-1222 in the US or 1-844-POISON-X (1-844-764-7669) in Canada.
Like all medications, Zyban may cause side effects. While Zyban is generally well-tolerated, it’s important to be aware of these potential side effects.
Difficulty sleeping
Dry mouth
Changes in appetite
Changes in taste
Nausea
Rash
As your body adjusts to the medication, some side effects may improve. If any effects persist or get worse, talk with your healthcare provider.
Seizures: Zyban lowers the seizure threshold, especially in individuals with risk factors (e.g., history of epilepsy, head trauma, or excessive alcohol use).
Severe Mood Changes: Increased anxiety, depression, suicidal thoughts, panic attacks, impulsivity, agitation, hostility, or aggressive behavior.
Cardiac Issues: Irregular heartbeats, fast heart rate, or significant blood pressure spikes.
Vision Problems: Blurred vision, tunnel vision, eye pain, seeing halos around lights.
Allergic Reactions: Symptoms such as hives, swelling of the face/throat, difficulty breathing, or a severe skin rash with blistering require emergency care.
Smoking cessation itself can cause mood instability. Antidepressants like bupropion (the active ingredient in Zyban) are also associated with suicidal thoughts or actions. This appears to be more prominent in adolescents and young adults.
Patients should be monitored for changes in mood and behavior, particularly in the early weeks of treatment.
Zyban may not be appropriate for individuals with a history of bipolar disorder, as it may increase the intensity or frequency of manic episodes.
If any serious or unusual symptoms occur, contact a healthcare provider immediately.
Zyban is not suitable for everyone. It carries specific risks and contraindications that must be considered before starting treatment.
Seizure Disorders: Zyban can trigger seizures and should never be used by individuals with epilepsy or a history of seizures.
Eating Disorders: Individuals with anorexia nervosa or bulimia have a higher risk of seizures when taking Zyban.
Alcohol or Sedative Withdrawal: People who have recently stopped drinking alcohol, benzodiazepines (e.g., Xanax, Valium), or seizure medications should avoid Zyban due to increased seizure risk.
Use of MAO Inhibitors: MAOIs (such as phenelzine, tranylcypromine, or selegiline) should not be used within 14 days before or after Zyban, as a dangerous drug interaction could occur.
Pregnancy and Breastfeeding: The effects of Zyban on unborn babies are unclear. Pregnant women should consult a doctor before using this medication.
Mental Health Conditions: Patients with a history of bipolar disorder, depression, or anxiety should be closely monitored for mood changes.
Heart Disease and Hypertension: Zyban can elevate blood pressure, especially when combined with nicotine patches.
To maintain Zyban’s effectiveness and ensure safety:
Store at room temperature (68°F to 77°F / 20°C to 25°C).
Keep away from moisture, heat, and direct sunlight.
Do not store in bathrooms due to humidity exposure.
Keep out of reach of children.
Properly dispose of expired or unused medication as directed by a pharmacist.
The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.