Prescription required. Product of Canada. Shipped from Canada. Simponi is also marketed internationally under the name Simponi Autoinjector.
Prescription required. Product of Canada. Shipped from Canada. Simponi is also marketed internationally under the name Simponi Syringe.
To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more
(goe lim' ue mab)Using golimumab injection may decrease your ability to fight infection and increase the risk that you will get a serious infection, including severe fungal, bacterial, or viral infections that spread through the body. These infections may need to be treated in a hospital and may cause death. Tell your doctor if you often get any type of infection or if you think you may have any type of infection now. This includes minor infections (such as open cuts or sores), infections that come and go (such as cold sores) and chronic infections that do not go away. Also tell your doctor if you have or have ever had diabetes, human immunodeficiency virus (HIV) , acquired immunodeficiency syndrome (AIDS), or any other condition that affects your immune system. You should also tell your doctor if you live or have ever lived in areas such as the Ohio or Mississippi river valleys where severe fungal infections are more common. Ask your doctor if you are not sure if these infections are common in your area. Tell your doctor if you are taking medications that decrease the activity of the immune system such as the following: abatacept (Orencia); anakinra (Kineret); methotrexate (Rheumatrex); rituximab (Rituxan); steroids including dexamethasone, methylprednisolone (Medrol), prednisolone (Prelone) and prednisone; tocilizumab (Actemra); and other TNF-blockers such as adalimumab (Humira), certolizumab (Cimzia), etanercept (Enbrel), and infliximab (Remicade). Your doctor will monitor you for signs of infection during and after your treatment. If you have any of the following symptoms before you begin your treatment or if you experience any of the following symptoms during or shortly after your treatment, call your doctor immediately: weakness; sweating; sore throat; cough; coughing up bloody mucus; fever; weight loss; extreme tiredness; diarrhea; stomach pain; warm, red, or painful skin; sores on the skin; painful, difficult, or frequent urination; or other signs of infection. You may be infected with tuberculosis (TB, a type of lung infection) or hepatitis B (a type of liver disease) but not have any symptoms of the disease. In this case, golimumab injection may increase the risk that your infection will become more serious and you will develop symptoms. Your doctor will perform a skin test to see if you have an inactive TB infection and may order blood tests to see if you have an inactive hepatitis B infection. If necessary, your doctor will give you medication to treat this infection before you start using golimumab injection. Tell your doctor if you have or have ever had TB or hepatitis B, if you have visited any country where TB is common, or if you have been around someone who has TB. If you have any of the following symptoms of TB, or if you develop any of these symptoms during your treatment, call your doctor immediately: cough, weight loss, loss of muscle tone, or fever. Also call your doctor immediately if you have any of these symptoms of hepatitis B or if you develop any of these symptoms during or after your treatment: excessive tiredness, yellowing of the skin or eyes, loss of appetite, nausea or vomiting, muscle aches, dark urine, clay-colored bowel movements, fever, chills, stomach pain, or rash. Some children, teenagers, and young adults who received golimumab injection and similar medications developed severe or life-threatening cancers including lymphoma (cancer that begins in the cells that fight infection). Some teenage and young adult males who took golimumab or similar medications developed hepatosplenic T-cell lymphoma (HSTCL), a very serious form of cancer that often causes death within a short period of time. Most of the people who developed HSTCL were being treated for Crohn's disease (a condition in which the body attacks the lining of the digestive tract, causing pain, diarrhea, weight loss, and fever) or ulcerative colitis (a condition which causes swelling and sores in the lining of the colon [large intestine] and rectum) with golimumab or a similar medication along with another medication called azathioprine (Imuran) or 6-mercaptopurine (Purinethol). Children and teenagers should not normally receive golimumab injection, but in some cases, a doctor may decide that golimumab injection is the best medication to treat a child's condition. If golimumab injection is prescribed for your child, you should talk to your child's doctor about the risks and benefits of using this medication. If your child develops any of these symptoms during his treatment, call his doctor immediately: unexplained weight loss; swollen glands in the neck, underarms, or groin; or easy bruising or bleeding. Talk to your doctor about the risks of receiving golimumab injection.
- rheumatoid arthritis (condition in which the body attacks its own joints causing pain, swelling, and loss of function),
- ankylosing spondylitis (condition in which the body attacks the joints of the spine and other areas causing pain and joint damage),
- psoriatic arthritis (condition that causes joint pain and swelling and scales on the skin).
- ulcerative colitis (a condition which causes swelling and sores in the lining of the colon [large intestine] and rectum) when other medications and treatments did not help or could not be tolerated.
Before using golimumab injection,
- tell your doctor and pharmacist if you are allergic to golimumab injection, any other medications, or any of the ingredients in golimumab injection. Ask your pharmacist or check the Medication Guide for a list of the ingredients. Also tell your doctor if you or the person who will be helping you inject golimumab injection are allergic to latex or rubber.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following medications: anticoagulants ('blood thinners') such as warfarin (Coumadin), cyclosporine (Gengraf, Neoral, Sandimmune), and theophylline (Theochron, Theolair, Uniphyl). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you have or have ever had cancer, psoriasis (a skin disease in which red scaly patches form on the skin), any condition that affects your nervous system such as multiple sclerosis (MS, a disease in which the nerves do not function properly causing weakness, numbness, loss of muscle coordination and problems with vision, speech, and bladder control) or Guillain Barre syndrome (weakness, tingling, and possible paralysis due to sudden nerve damage), a low number of any type of blood cell, or heart disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while using golimumab injection, call your doctor. If you use golimumab injection during your pregnancy, be sure to talk to your baby's doctor about this after your baby is born. Your baby may need to receive certain vaccines later than usual.
- do not have any vaccinations without talking to your doctor.
- redness, itching, bruising, pain, or swelling in the place where golimumab was injected
- chest pain
- shortness of breath
- swelling of the ankles or lower legs
- vision changes
- weakness, numbness, or tingling of the arms or legs
- red scaly patches or pus-filled bumps on the skin
- pain in the upper right part of the stomach
- easy bruising or bleeding
- pale skin
- rash on the cheeks or other part of the body
- sensitivity to the sun
- joint pain
- swelling of the eyes, face, lips, tongue, mouth, or throat
- difficulty breathing or swallowing
The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.