Buy Rinvoq Online (Upadacitinib)

(Upadacitinib)

Let's fill your order for Rinvoq!
Select your medication dosage:

Brand Name

Rinvoq 15mg Tablet

Prescription required. Can not be split. Product of Australia. Shipped from Australia.

$1,856.99 28 tablets ($66.32/ea)
$3,635.36 56 tablets ($64.92/ea)
$5,447.99 84 tablets ($64.86/ea)

Generic equivalent for Rinvoq

Sorry, we currently do not carry a generic option for this item.

What are generics?

Brand Name

Rinvoq 30mg Tablet

Prescription required. Can not be split. Product of Australia. Shipped from Australia.

$2,682.99 28 tablets ($95.82/ea)
$5,054.59 56 tablets ($90.26/ea)
$7,426.19 84 tablets ($88.41/ea)

Generic equivalent for Rinvoq

Sorry, we currently do not carry a generic option for this item.

What are generics?

Introduction

Rinvoq (upadacitinib) is a Janus kinase (JAK) inhibitor that suppresses immune system activity to reduce inflammation. It is prescribed for a range of chronic autoimmune inflammatory conditions, particularly in patients who have not responded to alternative biologic therapies (e.g., TNF blockers). Rinvoq is available as an oral extended-release tablet and as Rinvoq LQ, a liquid formulation for pediatric use. Doses are not interchangeable between forms, and changes should always be made with close monitoring by a healthcare provider.

Primary Indications

  • Rheumatoid Arthritis (RA): For adults with moderate to severe RA unresponsive to TNF inhibitors.

  • Psoriatic Arthritis (PsA): For adults with inadequate response to TNF inhibitors.

  • Atopic Dermatitis (Eczema): For adults and children 12+ years with refractory moderate-to-severe eczema.

  • Ulcerative Colitis (UC): For adults with moderate-to-severe UC not responsive to other treatments.

  • Crohn’s Disease (CD): For adults with refractory moderate-to-severe CD.

  • Ankylosing Spondylitis & Non-radiographic Axial Spondyloarthritis: For adults with spine-related inflammatory conditions.

  • Giant Cell Arteritis: In combination with steroids or as monotherapy after tapering.

  • Polyarticular Juvenile Idiopathic Arthritis (JIA): For children aged 2+ unresponsive to TNF blockers.

Rinvoq should not be combined with other biologic DMARDs or other potent immunosuppressants. 


To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more

Why Prescribed

Rinvoq is used to help manage chronic autoimmune and inflammatory diseases by:

  • Reducing inflammation and joint damage in arthritis

  • Improving skin symptoms in eczema

  • Controlling bowel inflammation in IBD (UC and Crohn’s)

  • Its oral formulation minimizes steroid dependence in vasculitis and arthritis 

Rinvoq offers a helpful alternative to biologic injections, especially for long-term disease management.

How to Use

Dosage and Administration

  • Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, Giant Cell Arthritis: 

  • Adults: 15 mg once daily

  • Children: Weight-based for ages 2+, depending on condition

  • Atopic Dermatitis:

  • Adults <65: Start at 15 mg once daily; may increase to 30 mg if needed

  • Adults ≥65: 15 mg daily

  • Children ≥12 years: Weight-based

  • Ulcerative Colitis:

  • Induction: 45 mg daily for 8 weeks

  • Maintenance: 15–30 mg daily

  • Crohn’s Disease:

  • Induction: 45 mg daily for 12 weeks

  • Maintenance: 15–30 mg daily

  • Juvenile Idiopathic Arthritis: 

  • Weight-based for ages 2+

Dosing recommendations may vary depending on individual needs. Take tablets whole with or without food. Do not crush or chew.

Missed Dose

Take as soon as remembered unless it’s near the next dose. Never double up.

Overdose

Call Poison Help (1-800-222-1222) in the US or 1-844-764-7669 in Canada, or seek emergency care.

Side Effects

Common Side Effects

The primary concern related to potent immunosuppressants like Rinvoq is an increased risk of infection. 

  • Upper respiratory tract infection (e.g., cold, flu)

  • Acne

  • Herpes simplex

  • Headache

  • Nausea

  • Fatigue, muscle pain

  • Low red or white blood cell counts

Serious Side Effects (Seek Immediate Help)

  • Heart attack, stroke, blood clots

  • Serious infections (e.g., pneumonia, shingles, TB)

  • GI perforation (severe abdominal pain, fever)

  • Hepatitis, liver damage

  • New or changing skin lesions (potential cancer)

  • Kidney issues (e.g., low urination, blood in urine)

  • Mental status changes, neurologic events

Warnings and Precautions

Do NOT take Rinvoq if:

  • You are allergic to upadacitinib

  • You are using another JAK inhibitor, biologic DMARD (e.g., Humira, Enbrel), or strong immunosuppressant (e.g., azathioprine)

Use With Caution If You Have:

  • Active/chronic infection

  • Liver disease or hepatitis

  • Cardiovascular risk (stroke, heart attack history)

  • GI disorders (e.g., diverticulitis)

  • Cancer history or immunosuppression

  • Are pregnant or breastfeeding

Boxed Warnings: Serious infections, cancer risk, blood clots, cardiovascular events, and mortality.

Before starting, it’s important to coordinate with your healthcare provider to ensure you have received all recommended vaccinations. A tuberculosis skin test and blood tests are also recommended to monitor baseline blood cell counts and liver function. 

Pregnancy and Breastfeeding

  • May cause harm to unborn babies. Use birth control during and for 4 weeks after treatment.

  • Do not breastfeed during treatment or within 6 days of the last dose.

  • Enroll in the pregnancy surveillance program if exposed.

Storage

  • Rinvoq Tablets: Store between 36°F and 77°F (2°C to 25°C) in the original container.

  • Rinvoq LQ (Liquid): Store between 36°F and 86°F (2°C to 30°C). Discard 60 days after opening.

Drug Interactions

Avoid:

  • Live vaccines (MMR, varicella, etc.)

  • Grapefruit and grapefruit juice

  • Concurrent use with:

  • Other immunosuppressants (e.g., azathioprine, cyclosporine)

  • Certain antibiotics (e.g., clarithromycin, rifampin)

  • Antifungals (e.g., ketoconazole)

  • NSAIDs and corticosteroids (increased risk of GI perforation)

Always tell your doctor about all medications and supplements you’re taking.


The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.