Before receiving ibandronate injection,
tell your doctor and pharmacist if you are allergic to ibandronate, any other medications, or any of the ingredients in ibandronate injection. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: angiogenesis inhibitors such as bevacizumab (Avastin), everolimus (Afinitor, Zortress), pazopanib (Votrient), sorafenib (Nexavar), or sunitinib (Sutent); cancer chemotherapy; and oral steroids such as dexamethasone, methylprednisolone (Medrol), and prednisone (Rayos). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
tell your doctor if you have hypocalcemia (lower than normal level of calcium in your blood). Your doctor will probably tell you not to use ibandronate injection.
tell your doctor if you are undergoing radiation therapy and if you have or have ever had anemia (condition in which the red blood cells do not bring enough oxygen to all the parts of the body); cancer; diabetes; any type of infection, especially in your mouth; problems with your mouth, teeth, or gums; high blood pressure; any condition that stops your blood from clotting normally; lower than normal levels of vitamin D; or heart or kidney disease.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. Also tell your doctor if you plan to become pregnant at any time in the future, because ibandronate may remain in your body for years after you stop using it. Call your doctor if you become pregnant during or after your treatment.
you should know that ibandronate injection may cause osteonecrosis of the jaw (ONJ, a serious condition of the jaw bone), especially if you have dental surgery or treatment while you are receiving the medication. A dentist should examine your teeth and perform any needed treatments, including cleaning or fixing ill-fitted dentures, before you start to receive ibandronate. Be sure to brush your teeth and clean your mouth properly while you are receiving ibandronate injection. Talk to your doctor before having any dental treatments while you are receiving this medication.
you should know that ibandronate injection may cause severe bone, muscle, or joint pain. You may begin to feel this pain within days, months, or years after you first receive ibandronate injection. Although this type of pain may begin after you have received ibandronate injection for some time, it is important for you and your doctor to realize that it may be caused by ibandronate. Call your doctor right away if you experience severe pain at any time during your treatment with ibandronate injection. Your doctor may stop giving you ibandronate injection and your pain may go away after you stop treatment with this medication.
talk to your doctor about other things you can do to prevent osteoporosis from developing or worsening. Your doctor will probably tell you to avoid smoking and drinking large amounts of alcohol and to follow a regular program of weight-bearing exercise.