Before taking sodium picosulfate, magnesium oxide, and anhydrous citric acid,
tell your doctor and pharmacist if you are allergic to sodium picosulfate, magnesium oxide, or anhydrous citric acid, any other medications, or any of the ingredients in sodium picosulfate, magnesium oxide, and anhydrous citric acid powder. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: angiotensin converting enzyme inhibitors (ACEIs) such as benazepril (Lotensin, in Lotrel), captopril (Capoten, in Capozide), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril, in Prinzide and Zestoretic), moexipril (Univasc, in Uniretic), perindopril (Aceon), quinapril (Accupril, in Accuretic and Quinaretic), ramipril (Altace), or trandolapril (Mavik, in Tarka); aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, others) and naproxen (Aleve, Naprosyn, others); angiotensin receptor blockers (ARBs) such as candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro, in Avalide), losartan (Cozaar, in Hyzaar), olmesartan (Benicar), telmisartan (Micardis), or valsartan (Diovan); carbamazepine (Carbatrol, Equetro, Tegretol); diuretics (water pills); medications for depression, mental illness, kidney disease, or seizures; steroids such as dexamethasone, methylprednisolone (Medrol), prednisolne (Prelone), or prednisone; or selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, in Symbyax), fluvoxamine, paroxetine (Paxil), and sertraline (Zoloft). Also tell your doctor if you are taking or have recently taken antibiotics. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
do not take any other laxatives during your treatment with sodium picosulfate, magnesium oxide, and anhydrous citric acid.
if you take any medications by mouth, take them at least 1 hour before you start taking sodium picosulfate, magnesium oxide, and anhydrous citric acid. If you are taking any of the following medications, take them 2 hours before you start taking sodium picosulfate, magnesium oxide, and anhydrous citric acid or 6 hours after you finish your treatment with this medication: digoxin (Lanoxin);chlorpromazine; fluoroquinolone antibiotics such as ciprofloxacin (Cipro, Proquin), gemifloxacin (Factive), levofloxacin (Levaquin), moxifloxacin (Avelox), norfloxacin (Noroxin), and ofloxacin; iron supplements; penicillamine (Cuprimine, Depen); and tetracycline.
tell your doctor if you have or have ever had a blockage in your stomach or intestine, an opening in the wall of your stomach or intestine, toxic megacolon (life-threatening widening of the intestine), any condition that stops food and fluid from being emptied from the stomach normally, or kidney disease. Your doctor may tell you not to take sodium picosulfate, magnesium oxide, and anhydrous citric acid.
tell your doctor if you have been drinking large amounts of alcohol or taking medications for anxiety or seizures and are now decreasing your use of these substances. Also tell your doctor if you have recently had a heart attack and if you have or have ever had heart failure, an irregular heartbeat, an enlarged heart, a prolonged QT interval (a rare heart problem that may cause irregular heartbeat, fainting, or sudden death), seizures, a low level of sodium in your blood, inflammatory bowel disease (conditions such as Crohn's disease (a condition in which the body attacks the lining of the digestive tract, causing pain, diarrhea, weight loss, and fever) and ulcerative colitis (a condition which causes swelling and sores in the lining of the colon [large intestine] and rectum) that cause swelling and irritation in all or part of the intestine), difficulty swallowing, or gastric reflux (condition in which backward flow of acid from the stomach causes heartburn and possible injury to the esophagus).
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding.