Zontivity (Vorapaxar sulfate)
To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more
Vorapaxar sulfate Information
(vor'' a pax' ar)
Vorapaxar may cause severe bleeding that can be life-threatening and even cause death. Tell your doctor if you have or have ever had a stroke or mini-stroke; bleeding in the brain; any type of blood or bleeding disorder; or a stomach ulcer. Your doctor will probably tell you not to take vorapaxar. Also tell your doctor if you currently have any unusual type of bleeding such as bleeding in the head, stomach, or intestines; if you have had a recent surgery or injury;or have kidney or liver disease. Tell your doctor and pharmacist if you are taking anagrelide (Agrylin); nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, others), indomethacin (Indocin, Tivorbex), ketoprofen, and naproxen (Aleve, Anaprox, others) taken on a regular basis; dabigatran (Pradaxa); dalteparin (Fragmin); enoxaparin (Lovenox); fondaparinux (Arixtra); heparin; rivaroxaban (Xarelto); selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil), and sertraline (Zoloft); and serotonin and norepinephrine reuptake inhibitors (SNRIs) such as duloxetine (Cymbalta), desvenlafaxine (Khedezla, Pristiq), milnacipran (Fetzima, Savella), and venlafaxine (Effexor); and warfarin (Coumadin, Jantoven). If you experience any of the following symptoms during your treatment and for at least 4 weeks after you stop taking the medication, call your doctor immediately: bleeding that is unexpected, severe, or that you cannot control; pink, red, or brown urine; vomiting blood or material that looks like coffee grounds; red or tarry black stools; coughing up blood or blood clots; nosebleeds; headache; dizziness; or weakness. Talk to your doctor about the risks of taking vorapaxar.-
Before taking vorapaxar,
- tell your doctor and pharmacist if you are allergic to vorapaxar, any other medications, or any of the ingredients in vorapaxar tablets. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: certain antifungals such as itraconazole (Sporanox, Onmel), ketoconazole (Nizoral), and posaconazole (Noxafil); boceprevir (Victrelis); carbamazepine (Carbatrol, Tegretol); clarithromycin (Biaxin, in PrevPac); conivaptan (Vaprisol); certain medications for human immunodeficiency virus (HIV) such as indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra), and saquinavir (Invirase); nefazodone; phenytoin (Dilantin, Phenytek); rifampin (Rifadin, Rimactane); telaprevir (Incivek); and telithromycin (Ketek); Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor what herbal products you are taking, especially St. Johns wort.
- tell your doctor if you have or have ever had any medical condition especially those listed in the IMPORTANT WARNING section.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking vorapaxar, call your doctor.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking vorapaxar.
- tiredness
- weakness
- pale skin
- cool hands and feet
The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.