Before taking fludrocortisone,
tell your doctor and pharmacist if you are allergic to fludrocortisone, aspirin, tartrazine (a yellow dye in some processed foods and drugs), or any other drugs.
tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially anticoagulants ('blood thinners') such as warfarin (Coumadin), arthritis medications, aspirin, cyclosporine (Neoral, Sandimmune), digoxin (Lanoxin), diuretics ('water pills'), estrogen (Premarin), ketoconazole (Nizoral), oral contraceptives, phenobarbital, phenytoin (Dilantin), rifampin (Rifadin), theophylline (Theo-Dur), and vitamins.
if you have a fungal infection (other than on your skin), do not take fludrocortisone without talking to your doctor.
tell your doctor if you have or have ever had liver, kidney, intestinal, or heart disease; diabetes; an underactive thyroid gland; high blood pressure; mental illness; myasthenia gravis; osteoporosis; herpes eye infection; seizures; tuberculosis (TB); or ulcers.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking fludrocortisone, call your doctor.
if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking fludrocortisone.
if you have a history of ulcers or take large doses of aspirin or other arthritis medication, limit your consumption of alcoholic beverages while taking this drug. Fludrocortisone makes your stomach and intestines more susceptible to the irritating effects of alcohol, aspirin, and certain arthritis medications. This effect increases your risk of ulcers.