Before using umeclidinium and vilanterol,
tell your doctor and pharmacist if you are allergic to umeclidinium, vilanterol, any other medications, milk protein, or any of the ingredients in umeclidinium and vilanterol inhalation. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antifungals such as itraconazole (Sporanox), ketoconazole (Nizoral), and voriconazole (Vfend); antihistamines; atropine; beta-blockers such as atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), and propranolol (Inderal); clarithromycin (Biaxin); conivaptan (Vaprisol); diuretics ('water pills'); HIV protease inhibitors such as indinavir (Crixivan), lopinavir (in Kaletra), nelfinavir (Viracept), ritonavir (Norvir), and saquinavir (Invirase); other LABAs such as arformoterol (Brovana), formoterol (Foradil, in Symbicort), indacaterol (Arcapta), or salmeterol (in Advair, Serevent); other medications for COPD including aclidinium (Tudorza Pressair), ipratropium (Atrovent HFA), and tiotropium (Spiriva); medications for irritable bowel disease, motion sickness, Parkinson's disease, ulcers, or urinary problems; nefazodone (Serzone); telithromycin (Ketek); and troleandomycin (TAO). Also tell your doctor and pharmacist if you are taking the following medications or have stopped taking them during the past 2 weeks: antidepressants such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); and monoamine oxidase (MAO) inhibitors, including isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl), and tranylcypromine (Parnate). Many other medications may also interact with umeclidinium and vilanterol, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
tell your doctor if you have or have ever had high blood pressure, irregular heartbeat, seizures, thyroid problems, diabetes, glaucoma (an eye disease), prostate or bladder problems, or heart or liver disease.
tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while using umeclidinium and vilanterol, call your doctor.
if you are having surgery, including dental surgery, tell the doctor or dentist that you are using umeclidinium and vilanterol.