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(Sodium Polystyrene Sulfonate)
Prescription required. Can not be split. Product of Canada. Shipped from Canada.
Sodium polystyrene sulfonate (SPS), commonly marketed under the brand name Kayexalate, is used to treat hyperkalemia (elevated potassium levels in the blood). It is available in several formulations:
Liquid suspension: Administered orally or as an enema.
Powder form: Requires mixing into a suspension before use.
The typical dosing frequency ranges from one to four times daily, depending on the healthcare provider's instructions. Common side effects include gastrointestinal issues such as nausea, vomiting, constipation, or diarrhea, as well as reduced appetite. Always follow your provider's guidance for proper use, as these instructions are guided specifically by individual needs.
To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more
Sodium polystyrene sulfonate (SPS) (or Kayexalate) comes in two forms:
Powder: Contains 3.5 grams per level teaspoon for reconstitution into a suspension.
Liquid Suspension: Comes in a 15 g per 60 mL bottle.
Although the powder form requires mixing before use, both forms can deliver the same dosages. Your dose depends on your potassium levels, how well you're responding to the medication, and whether you experience any side effects.
Adults:
Oral: The typical dose is 15 grams, taken 1 to 4 times daily.
Rectal (Enema): The typical dose is 30 to 50 grams, inserted into the rectum every 6 hours.
Children:
A doctor will determine if SPS (or Kayexalate) is safe for your child and calculate the correct dose based on their blood potassium levels.
Sodium polystyrene sulfonate (SPS) (or Kayexalate) can interact with certain medications or supplements. Always inform your doctor and pharmacist about all your medications or supplements, including over-the-counter products, vitamins, and herbal supplements. Below are some important interactions:
Medications That May Alter or be Altered by Kayexalate Therapy (May Require Dose Adjustment):
Antacids
Magnesium hydroxide
Digoxin
Sorbitol
Lithium
Thyroxine
Your doctor may adjust doses or monitor you closely if you take any of these medications with Kayexalate. Always follow your healthcare provider's advice.
Some side effects may improve as your body adjusts to the medication. Contact your healthcare provider immediately if these symptoms persist or worsen over time.
Common Side Effects:
Low appetite
Nausea
Vomiting
Constipation
Diarrhea
Other Side Effects:
Gut irritation
Blockage in the gut (fecal impaction)
The risk of developing a gut blockage may increase when administered rectally (i.e., enema). Following the dosage guidelines provided by your doctor is essential. Kayexalate is associated with electrolyte disturbances, and taking more than recommended increases this risk. Electrolyte disturbances can manifest in many ways, ranging from fluid retention (e.g., swelling around feet and ankles) to more serious effects, including irregular heart rhythm or seizures.
Serious Side Effects:
Get medical help right away if you experience any of the following:
Intestinal necrosis (low blood flow to the stomach and intestines), characterized by:
Bleeding in stool
Nausea, vomiting, constipation, or diarrhea
Fever
Stomach pain
Low electrolyte levels, characterized by:
Muscle cramps or pain
Numbness or tingling
Weakness or fatigue
Shortness of breath
Confusion
Overdose Symptoms:
Overdosage can lead to dangerous electrolyte disturbances, including low blood potassium, calcium, and magnesium levels. These disturbances have the potential to be life-threatening. Get emergency help immediately if you notice any of the following signs of an overdose:
Dizziness or lightheadedness
Drowsiness or fainting
Fast, slow, or irregular heartbeat
Muscle spasms or twitching
Trembling or pounding pulse
The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.