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(Mirtazapine)
Prescription required. Can not be split. Product of Australia. Shipped from Australia. Remeron is also marketed internationally under the name Axit.
Prescription required. May be split. Product of UK/EU. Shipped from United Kingdom.
Prescription required. May be split. Product of Australia. Shipped from Australia. Remeron is also marketed internationally under the name Avanza.
Prescription required. May be split. Product of UK/EU. Shipped from United Kingdom.
Prescription required. May be split. Product of UK/EU. Shipped from United Kingdom.
Remeron (Mirtazapine) is a prescription medication used to treat Major Depressive Disorder (MDD) in adults. Classified as a tetracyclic antidepressant, it is thought to work by balancing neurotransmitters such as serotonin and norepinephrine in the brain. While the exact mechanism is not fully understood, Remeron helps improve mood, sleep, and appetite in individuals experiencing moderate to severe depression. Remeron is also sometimes recommended by healthcare providers to help treat conditions like insomnia, headaches, and fibromyalgia.
Remeron is prescribed for major depressive disorder and is often chosen when symptoms include:
Significant sleep disturbances (insomnia)
Appetite loss and unintended weight loss
Anxiety or agitation
Poor response to other antidepressants
It may be favored in some instances for its sedating effects and lower risk of sexual side effects compared to SSRIs and SNRIs. When prescribed for depression, it’s often an option after treatments with SSRIs or SNRIs are not well-tolerated.
To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more
Take Remeron exactly as prescribed by your healthcare provider. Standardized instructions often include:
Initial dose is usually 15 mg taken once daily, typically at bedtime due to drowsiness
Dose may be increased gradually to a maximum of 45 mg/day
Can be taken with or without food
For orally disintegrating tablets (SolTab), place on the tongue and allow it to dissolve; do not chew or crush
Continue taking Remeron even if the symptoms being managed do not seem to improve right away—improvements may take 2–4 weeks.
Before starting Remeron, tell your doctor if you have a history of:
Bipolar disorder, suicidal thoughts, or severe depression
Seizures, liver or kidney disease
Glaucoma or heart problems (including a history of arrhythmias or QT prolongation)
Low white blood cell counts or low sodium levels
Do not take Remeron if you:
Are allergic to mirtazapine
Are taking or have recently taken an MAO inhibitor (within 14 days)
Take supplements containing tryptophan
Avoid drinking alcohol and discuss with your provider before stopping the medication. Sudden discontinuation can lead to withdrawal symptoms such as dizziness, sweating, nausea, or mood changes.
It’s important to note that Remeron can interact with a variety of medications and over-the-counter products. Talk with your healthcare providers about all of the products you use to ensure they can be used safely together. In some instances, dosage adjustments or alternatives may be needed to ensure safety.
No special diet is required while taking Remeron
However, be aware that it may increase appetite and lead to weight gain
If you have phenylketonuria (PKU), avoid orally disintegrating tablets (SolTab), which may contain phenylalanine
If you miss a dose:
Take it as soon as you remember unless it’s nearly time for your next dose
Do not take two doses at once
Resume your regular schedule the next day
Drowsiness or sedation
Dizziness
Increased appetite and weight gain
In some instances, mirtazapine may be specifically chosen for individuals who are unintentionally losing weight due to its ability to help stimulate appetite.
Allergic reactions (rash, swelling, difficulty breathing)
Low white blood cell count (fever, sore throat, flu-like symptoms)
Seizures
Serotonin syndrome (confusion, fever, tremors, nausea, hallucinations)
Low sodium levels (headache, vomiting, weakness, confusion)
Contact your doctor immediately if you experience suicidal thoughts, panic attacks, or mood changes. Remeron, like other antidepressants, has been associated with an increase in suicidal thoughts and behavior, particularly in pediatric and young adult patients. Supportive monitoring during a treatment transition is critical.
Store Remeron at room temperature (68–77°F or 20–25°C)
Keep away from light, heat, and moisture
Keep in the original container with the lid tightly closed
Keep out of reach of children and pets
Do not share this medication with others
Tell your provider about all current medications, including:
Antidepressants, opioids, sedatives
Herbal supplements (e.g., St. John’s Wort)
Migraine drugs (e.g., sumatriptan)
Antibiotics, antifungals, seizure medications
Remeron may cause drowsiness, so avoid driving or operating machinery until you know how it affects you
Inform your doctor if you become pregnant, plan to become pregnant, or are breastfeeding
For questions or to report side effects, contact your provider or call the FDA at 1-800-FDA-1088.
Mirtazapine (mir taz' a peen) Remeron® Remeron® SolTab A small number of children, teenagers, and young adults (up to 24 years of age) who took antidepressants ('mood elevators') such as mirtazapine during clinical studies became suicidal (thinking about harming or killing oneself or planning or trying to do so). Children, teenagers, and young adults who take antidepressants to treat depression or other mental illnesses may be more likely to become suicidal than children, teenagers, and young adults who do not take antidepressants to treat these conditions. However, experts are not sure about how great this risk is and how much it should be considered in deciding whether a child or teenager should take an antidepressant. Children younger than 18 years of age should not normally take mirtazapine, but in some cases, a doctor may decide that mirtazapine is the best medication to treat a child's condition. You should know that your mental health may change in unexpected ways when you take mirtazapine or other antidepressants even if you are an adult over 24 years of age. You may become suicidal, especially at the beginning of your treatment and any time that your dose is increased or decreased. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: new or worsening depression; thinking about harming or killing yourself, or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling asleep or staying asleep; aggressive behavior; irritability; acting without thinking; severe restlessness; and frenzied abnormal excitement. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor if you are unable to seek treatment on your own. Your healthcare provider will want to see you often while you are taking mirtazapine, especially at the beginning of your treatment. Be sure to keep all appointments for office visits with your doctor. The doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with mirtazapine. Read the information carefully and ask your doctor or pharmacist if you have any questions. You also can obtain the Medication Guide from the FDA website: http://www.fda.gov/Drugs/DrugSafety/InformationbyDrugClass/UCM096273. No matter what your age, before you take an antidepressant, you, your parent, or your caregiver should talk to your doctor about the risks and benefits of treating your condition with an antidepressant or with other treatments. You should also talk about the risks and benefits of not treating your condition. You should know that having depression or another mental illness greatly increases the risk that you will become suicidal. This risk is higher if you or anyone in your family has or has ever had bipolar disorder (mood that changes from depressed to abnormally excited) or mania (frenzied, abnormally excited mood) or has thought about or attempted suicide. Talk to your doctor about your condition, symptoms, and personal and family medical history. You and your doctor will decide what type of treatment is right for you.
Mirtazapine is used to treat depression. Mirtazapine is in a class of medications called antidepressants. It works by increasing certain types of activity in the brain to maintain mental balance.
Mirtazapine comes as a tablet and as a disintegrating tablet to take by mouth. It usually is taken once a day at bedtime. It may be taken with or without food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take mirtazapine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. To take a mirtazapine disintegrating tablet, open the blister pack with dry hands and place the tablet on your tongue. The tablet will disintegrate on the tongue and can be swallowed with saliva. No water is needed to swallow disintegrating tablets. Once the tablet is removed from the blister pack, it cannot be stored. Do not split mirtazapine disintegrating tablets. It may take several weeks or longer for you to feel the full benefit of mirtazapine. Continue to take mirtazapine even if you feel well. Do not stop taking mirtazapine without talking to your doctor. Your doctor probably will decrease your dose gradually.
Before taking mirtazapine, tell your doctor and pharmacist if you are allergic to mirtazapine, any other medications, or any of the ingredients in mirtazapine tablets or disintegrating tablets. Ask your doctor or pharmacist for a list of the ingredients. tell your doctor if you are taking a monoamine oxidase (MAO) inhibitor such as isocarboxazid (Marplan), linezolid (Zyvox), methylene blue, phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate) or if you have stopped taking an MAO inhibitor within the past 14 days. Your doctor will probably tell you not to take mirtazapine. If you stop taking mirtazapine, you should wait at least 14 days before you start to take an MAO inhibitor. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); antidepressants such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin, imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); certain antifungals such as ketoconazole (Nizoral); buspirone; carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, other); cimetidine (Tagamet); diazepam (Valium); erythromycin (E.E.S., E-mycin, Erythrocin); fentanyl (Abstral, Actiq, Fentora, Onsolis, others); lithium (Eskalith, Lithobid); medications for migraine headaches such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), and zolmitriptan (Zomig); certain medications to treat HIV; medications for anxiety and seizures; nefazodone; phenytoin (Dilantin); rifampin (Rimactane, Rifadin, in Rifater, in Rifamate); sedatives; selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil, Pexeva), and sertraline (Zoloft); selective serotonin and norepinephrine reuptake inhibitors (SNRIs) such as desvenlafaxine (Pristiq), duloxetine (Cymbalta), and venlafaxine (Effexor); sleeping pills; tramadol (Ultram); and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor what herbal products you are taking, especially St. John's wort and tryptophan. tell your doctor if you have or have ever had a heart attack, low blood pressure, heart, kidney, or liver disease, or high cholesterol. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking mirtazapine, call your doctor. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking mirtazapine. you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you. remember that alcohol can add to the drowsiness caused by this medication. if you have phenylketonuria (PKU, an inherited condition in which a special diet must be followed to prevent mental retardation), you should know that the orally disintegrating tablets contain aspartame that forms phenylalanine. you should know that mirtazapine may cause angle-closure glaucoma (a condition where the fluid is suddenly blocked and unable to flow out of the eye causing a quick, severe increase in eye pressure which may lead to a loss of vision). Talk to your doctor about having an eye examination before you start taking this medication. If you have nausea, eye pain, changes in vision, such as seeing colored rings around lights, and swelling or redness in or around the eye, call your doctor or get emergency medical treatment right away.
Unless your doctor tells you otherwise, continue your normal diet.
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Mirtazapine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: drowsiness dizziness anxiousness confusion increased weight and appetite dry mouth constipation nausea vomiting Some side effects can be serious. If you experience any of the following symptoms or those listed in the IMPORTANT WARNING or SPECIAL PRECAUTIONS section, call your doctor immediately or get emergency medical treatment: flu-like symptoms, fever, chills, sore throat, mouth sores, or other signs of infection chest pain fast heartbeat seizures Mirtazapine may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to mirtazapine. Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.