Before taking emtricitabine, rilpivirine, and tenofovir,
tell your doctor and pharmacist if you are allergic to emtricitabine, rilpivirine, and tenofovir, any other medications, or any of the ingredients in emtricitabine, rilpivirine, and tenofovir tablets. Ask your pharmacist for a list of the ingredients.
tell your doctor if you are taking adefovir (Hepsera), carbamazepine (Carbatrol, Equetro, Tegretol, others), dexamethasone, dexlansoprazole (Dexilant), esomeprazole (Nexium, Vimovo), lansoprazole (Prevacid, in Prevpac), omeprazole (Prilosec, in Zegerid), oxcarbazepine (Oxtellar XR, Trileptal), pantoprazole (Protonix), phenobarbital, phenytoin (Dilantin, Phenytek), rabeprazole (AcipHex), rifampin (Rifadin, Rimactane, in Rifamate, in Rifater), rifapentine (Priftin), or St. John's wort. Your doctor will probably tell you not to take emtricitabine, rilpivirine, and tenofovir if you are taking one or more of these medications.
tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: amiodarone (Cordarone, Nexterone, Pacerone); antibiotics such as clarithromycin (Biaxin, in Prevpac), erythromycin (E.E.S., Ery-Tab, Erythrocin, others), gentamicin, and telithromycin (Ketek); antifungal medications such as fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ketoconazole (Extina, Nizoral), posaconazole (Noxafil), and voriconazole (Vfend); anti-tuberculosis (anti-TB) medications such as rifabutin (Mycobutin) and rilpivirine (Edurant); antiviral medications such as acyclovir (Sitavig, Zovirax), cidofovir, ganciclovir (Cytovene), valacyclovir (Valtrex), and valganciclovir (Valcyte); aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); cyclosporine (Gengraf, Neoral, Sandimmune); other medications for HIV or AIDS; and methadone (Dolophine). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
if you are taking antacids containing calcium, magnesium, or aluminum (Maalox, Mylanta, Tums, others), take the antacid 2 hours before or at least 4 hours after you take emtricitabine, rilpivirine, and tenofovir.
if you are taking a medication for indigestion, heartburn, or ulcers such as cimetidine (Tagamet), famotidine (Pepcid, in Duexis), nizatidine (Axid), or ranitidine (Zantac), take it at least 12 hours before or at least 4 hours after emtricitabine, rilpivirine, and tenofovir.
tell your doctor if you have or have ever had the conditions mentioned in the IMPORTANT WARNING section, kidney disease, depression or other mental illness, bone problems including osteoporosis (a condition in which the bones become thin and weak and break easily) or bone fractures, or any type of infection that does not go away or that comes and goes such as tuberculosis (TB; a type of lung infection) or cytomegalovirus (CMV; a viral infection that may cause symptoms in people with weak immune systems).
tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking emtricitabine, rilpivirine, and tenofovir, call your doctor. You should not breastfeed if you are infected with HIV or if you are taking emtricitabine, rilpivirine, and tenofovir.
you should know that emtricitabine, rilpivirine, and tenofovir may cause changes in your thoughts, behavior, or mental health. Call your doctor immediately if you develop any of the following symptoms while you are taking emtricitabine, rilpivirine, and tenofovir: new or worsening depression; feeling sad, hopeless, anxious, or restless; or thinking about killing yourself or planning or trying to do so.
you should be aware that your body fat may increase or move to different areas of your body, such as your upper back, neck (''buffalo hump''), breasts, and around your stomach. You may notice a loss of body fat from your face, legs, and arms.
you should know that while you are taking medications to treat HIV infection, your immune system may get stronger and begin to fight other infections that were already in your body. This may cause you to develop symptoms of those infections. If you have new or worsening symptoms at any time during your treatment with emtricitabine, rilpivirine, and tenofovir, be sure to tell your doctor.