Before taking isavuconazonium,
tell your doctor and pharmacist if you are allergic to isavuconazonium, fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole, any other medications, or any of the ingredients in isavuconazonium capsules. Ask your pharmacist for a list of the ingredients.
tell your doctor if you are taking carbamazepine (Carbatrol, Tegretol), ketoconazole (Nizoral), phenobarbital, rifampin (Rifadin, Rifamate), ritonavir (Norvir, in Kaletra), or St. John's wort. Your doctor will probably tell you not to take isavuconazonium if you are taking one or more of these medications.
tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: atorvastatin (Lipitor), bupropion (Aplenzin, Forfivo XL, Wellbutrin, Zyban), cyclosporine (Gengraf, Neoral, Sandimmune), digoxin (Digitek, Lanoxicaps, Lanoxin), midazolam, mycophenolate mofetil (CellCept), sirolimus (Rapamune), or tacrolimus (Prograf). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with isavuconazonium, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
tell your doctor if you or anyone in your family has or has ever had short QT syndrome (condition that increases the risk of irregular heartbeat, dizziness, fainting, or sudden death). Your doctor will probably tell you not to take isavuconazonium.
tell your doctor if you have or have ever had heart or liver problems.
tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking isavuconazonium, call your doctor.