Before taking dasatinib,
tell your doctor and pharmacist if you are allergic to dasatinib, any other medications, or any of the ingredients in dasatinib tablets. Ask your pharmacist for a list of the ingredients.
tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: anticoagulants (''blood thinners'') such as warfarin (Coumadin, Jantoven); anthracycline medications for cancer such as daunorubicin (Cerubidine), doxorubicin (Doxil), and epirubicin (Ellence); certain antifungals such as ketoconazole (Nizoral), itraconazole (Onmel, Sporanox), and voriconazole (Vfend); clarithromycin (Biaxin, in PrevPac); dexamethasone; certain medications used to treat human immunodeficiency virus (HIV) such as atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), and saquinavir (Invirase); certain medications for irregular heartbeat such as amiodarone (Nexterone, Pacerone), disopyramide (Norpace), dofetilide (Tikosyn), flecainide (Tambocor), mexiletine (Mexitil), procainamide, propafenone (Rythmol), quinidine (in Nuedexta), and sotalol (Betapace, Betapace AF, Sorine), medications to reduce stomach acid such as cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), ranitidine (Zantac), esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), and rabeprazole (AcipHex); nefazodone; rifampin (Rimactane, Rifadin, in Rifater, in Rifamate); and telithromycin (Ketek); Many other medications may also interact with dasatinib, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
if you are taking antacids, such as aluminum hydroxide/magnesium hydroxide (Maalox), calcium carbonate (Tums), or calcium carbonate and magnesium (Rolaids), take them 2 hours before or 2 hours after you take dasatinib.
tell your doctor what herbal products you are taking, especially St. John's wort.
tell your doctor if you have or have ever had lactose intolerance (inability to digest dairy products), low levels of potassium or magnesium in your blood, long QT syndrome (a heart condition that may cause dizziness, fainting, or irregular heartbeat), problems with your immune system, or liver, lung, or heart disease.
tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while you are taking dasatinib and for 30 days after your final dose. Talk to your doctor about birth control methods that will work for you. If you become pregnant while taking dasatinib, call your doctor. Women who are pregnant should not handle crushed or broken dasatinib tablets. Dasatinib may harm the fetus.
do not breastfeed while taking dasatinib and for 2 weeks after your final dose.
you should know that this medication may decrease fertility in men and women. Talk to your doctor about the risks of taking dasatinib.
if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking dasatinib.