Afinitor (Everolimus)
Afinitor
2.5mg Tablet
Prescription required. Can not be split. Product of Australia. Shipped from Australia.
Afinitor
5mg Tablet
Prescription required. Can not be split. Product of Australia. Shipped from Australia.
Afinitor
10mg Tablet
Prescription required. Can not be split. Product of Australia. Shipped from Australia.
Generic equivalents for Afinitor... What are generics?
Everolimus
2.5mg Tablet
Prescription required. Can not be split. Product of Canada. Shipped from Canada.
Everolimus
5mg Tablet
Prescription required. Can not be split. Product of Canada. Shipped from Canada.
Everolimus
10mg Tablet
Prescription required. Can not be split. Product of Canada. Shipped from Canada.
To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more
Everolimus Information
(e'' ver oh' li mus)
Taking everolimus may decrease your ability to fight infection from bacteria, viruses, and fungi and increase the risk that you will get a serious or life-threatening infection. If you have had hepatitis B (a type of liver disease) in the past, your infection may become active and you may develop symptoms during your treatment with everolimus. Tell your doctor if you have or have ever had hepatitis B or if you have or think you may have any type of infection now. Tell your doctor and pharmacist if you are taking other medications that suppress the immune system such as azathioprine (Imuran), cyclosporine (Gengraf, Neoral, Sandimmune), dexamethasone (Decadron, Dexpak), methotrexate (Rheumatrex, Trexall), prednisolone (Orapred, Pediapred, Prelone), prednisone (Sterapred), sirolimus (Rapamune), and tacrolimus (Prograf). If you experience any of the following symptoms, call your doctor immediately: excessive tiredness; yellowing of the skin or eyes; loss of appetite; nausea; joint pain; dark urine; pale stools; pain in the upper right part of the stomach; rash; difficult, painful, or frequent urination; ear pain or drainage; sinus pain and pressure; or sore throat, cough, fever, chills, feeling unwell or other signs of infection. Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests to check your body's response to everolimus. Talk to your doctor about the risks of taking everolimus. For patients who are taking everolimus to prevent transplant rejection: You must take everolimus under the supervision of a doctor who is experienced in taking care of transplant patients and giving medications that suppress the immune system. The risk that you will develop cancer, especially lymphoma (cancer of a part of the immune system) or skin cancer is increased during your treatment with everolimus. Tell your doctor if you or anyone in your family has or has ever had skin cancer or if you have fair skin. To reduce your risk of skin cancer, plan to avoid unnecessary or prolonged exposure to sunlight or ultraviolet light (tanning beds and sunlamps) and to wear protective clothing, sunglasses, and sunscreen during your treatment. If you experience any of the following symptoms, call your doctor immediately: a red, raised, or waxy area on the skin; new sores, bumps, or discoloration on the skin; sores that do not heal; lumps or masses anywhere in your body; skin changes; night sweats; swollen glands in the neck, armpits, or groin; trouble breathing; chest pain; or weakness or tiredness that does not go away. Taking everolimus may increase the risk that you will develop certain very rare and serious infections, including infection with the BK virus, a serious virus that may damage the kidneys and cause a transplanted kidney to fail), and progressive multifocal leukoencephalopathy (PML; a rare infection of the brain that cannot be treated, prevented, or cured and that usually causes death or severe disability). Call your doctor immediately if you experience any of the following symptoms of PML: weakness on one side of the body that worsens over time; clumsiness of the arms or legs; changes in your thinking, walking, balance, speech, eyesight, or strength that last several days; headaches; seizures; confusion; or personality changes. Everolimus may cause a blood clot in the blood vessels of your transplanted kidney. This is most likely to happen within the first 30 days after your kidney transplant and may cause the transplant to be unsuccessful. If you experience any of the following symptoms, call your doctor immediately: pain in your groin, lower back, side, or stomach; decreased urination or no urination; blood in your urine; dark-colored urine; fever; nausea; or vomiting. Taking everolimus in combination with cyclosporine could cause damage to your kidneys. In order to reduce this risk, your doctor will adjust the dose of cyclosporine and monitor the levels of the medications and how your kidneys are working. If you experience either of the following symptoms, call your doctor immediately: decreased urination or swelling of the arms, hands, feet, ankles, or lower legs. In clinical studies, more people who took everolimus died during the first few months after receiving a heart transplant than people who did not take everolimus. If you have received a heart transplant, talk to your doctor about the risks of taking everolimus.-
Before taking everolimus,
- tell your doctor and pharmacist if you are allergic to everolimus, sirolimus (Rapamune), temsirolimus (Torisel), any other medications, or any of the ingredients in everolimus tablets. Ask your pharmacist for a list of the ingredients.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc) perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik); amprenavir (Agenerase), atazanavir (Reyataz),aprepitant (Emend), carbamazepine (Carbatrol, Epitol, Tegretol),clarithromycin (Biaxin, in Prevpac), digoxin (Digitek, Lanoxicaps, Lanoxin), diltiazem (Cardizem, Dilacor, Tiazac), efavirenz (in Atripla, Sustiva), erythromycin (E.E.S., E-Mycin, Erythrocin), fluconazole (Diflucan), fosamprenavir (Lexiva), indinavir (Crixivan), itraconazole (Sporanox), ketoconazole (Nizoral), nelfinavir (Viracept), nefazodone, nevirapine (Viramune), nicardipine (Cardene), phenobarbital (Luminal), phenytoin (Dilantin, Phenytek), rifabutin (Mycobutin), rifampin (Rifadin, in Rifamate, in Rifater), rifapentine (Priftin), ritonavir (Norvir, in Kaletra), saquinavir (Invirase),telithromycin (Ketek), verapamil (Calan, Covera, Isoptin, Verelan).and voriconazole (Vfend). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with everolimus, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
- tell your doctor what herbal products you are taking, especially St. John's wort.
- tell your doctor if you have or have ever had diabetes or high blood sugar; high levels of cholesterol or triglycerides in your blood; kidney or liver disease; or any condition that prevents you from digesting foods containing sugar, starch, or dairy products normally.
- tell your doctor if you are pregnant or plan to become pregnant If you are a woman who is able to become pregnant, you must use effective birth control during your treatment and for 8 weeks after your final dose.. If you are male with a female partner who is pregnant or could become pregnant, you must use effective birth control during your treatment and for 4 weeks after your final dose. Talk to your doctor about methods of birth control that will work for you. If you or your partner become pregnant while taking everolimus, call your doctor. Everolimus may harm the fetus.tell your doctor if you are breast feeding. Do not breast-feed during your treatment and for 2 weeks after your final dose.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking everolimus.
- do not have any vaccinations without talking to your doctor. During your treatment with everolimus, you should avoid close contact with other people who have recently been vaccinated.
- talk to your child's doctor about vaccinations that your child may need to receive before beginning his or her treatment with everolimus.
- you should know that you may develop sores or swelling in your mouth during your treatment with everolimus, especially during the first 8 weeks of treatment. When you start treatment with everolimus, your doctor may prescribe a certain mouthwash to reduce the chance that you will get mouth ulcers or sores and to reduce their severity. Follow your your doctor's instructions on how to use this mouthwash. Tell your doctor if you develop sores or feel pain in your mouth. . You should not use any mouthwash without talking to your doctor or pharmacist because certain types of mouthwash that contain alcohol, peroxide, iodine, or thyme can worsen the sores and swelling.
- you should know that wounds or cuts, including the cut in the skin made during a kidney transplant may heal more slowly than normal or may not heal properly during your treatment with everolimus. Call your doctor right away if the cut in the skin from your kidney transplant or any other wound becomes warm, red, painful, or swollen; fills with blood, fluid, or pus; or begins to open.
- diarrhea
- constipation
- change in ability to taste food
- weight loss
- dry mouth
- weakness
- headache
- difficulty falling asleep or staying asleep
- nosebleed
- dry skin
- acne
- problems with nails
- hair loss
- pain in the arms, legs, back or joints
- muscle cramps
- missed or irregular menstrual periods
- heavy menstrual bleeding
- difficulty getting or keeping an erection
- anxiety
- aggression or other changes in behavior
- hives
- itching
- swelling of the hands, feet, arms, legs, eyes, face, mouth, lips, tongue, or throat
- hoarseness
- difficulty breathing or swallowing
- wheezing
- flushing
- chest pain
- extreme thirst or hunger
- unusual bleeding or bruising
- pale skin
- fast or irregular heartbeat
- dizziness
- seizures
The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.