Before taking ofloxacin,
tell your doctor and pharmacist if you are allergic or have had a severe reaction to ofloxacin; other quinolone or fluoroquinolone antibiotics such as ciprofloxacin (Cipro), gatifloxacin (Tequin) (not available in the United States), gemifloxacin (Factive), Levofloxacin (Levaquin), lomefloxacin (Maxaquin) (not available in the United States), moxifloxacin (Avelox), nalidixic acid (NegGram) (not available in the United States), norfloxacin (Noroxin) (not available in the United States), and sparfloxacin (Zagam) (not available in the United States); or any other medications.
tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: other antibiotics; anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); certain antidepressants; antipsychotics (medications to treat mental illness); cimetidine (Tagamet); cyclosporine (Gengraf, Neoral, Sandimmune); diuretics ('water pills'); insulin and oral medications for diabetes such as glyburide (DiaBeta, Glynase, in Glucovance); certain medications for irregular heartbeat such as amiodarone (Cordarone, Nexterone, Pacerone), quinidine, procainamide , and sotalol (Betapace, Betapace AF, Sorine, Sotylize); nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin, others) and naproxen (Aleve, Naprosyn, others); probenecid (Probalan in Col-Probenecid, ); and theophylline (Elixophyllin, Theo-24, Uniphyl, others). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
if you are taking antacids containing aluminum, calcium, or magnesium (Maalox, Mylanta, Tums, others); didanosine (Videx) solution; sucralfate (Carafate); or supplements or multivitamins containing iron or zinc, take ofloxacin 2 hours before or 2 hours after you take these medications.
tell your doctor if you or anyone in your family has or has ever had a prolonged QT interval (a rare heart problem that may cause irregular heartbeat, fainting, or sudden death) or if you have or have ever had an irregular or slow heartbeat or heart attack and if you have or have ever had a low level of potassium or magnesium in your blood, a recent heart attack, diabetes, or liver disease.
tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking ofloxacin, call your doctor.
Do not drive a car, operate machinery, or participate in activities requiring alertness or coordination until you know how ofloxacin affects you.
plan to avoid unnecessary or prolonged exposure to sunlight and ultraviolet light (tanning beds and sunlamps) and to wear protective clothing, sunglasses, and sunscreen. Ofloxacin may make your skin sensitive to sunlight or ultraviolet light. If your skin becomes reddened, swollen, or blistered, call your doctor.