Epclusa (Sofosbuvir / Velpatasvir)
Prescription required. May be split. Product of Canada. Shipped from Canada.
To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more
Sofosbuvir / Velpatasvir Information
(soe fos' bue vir) (vel pat' as vir)You may already be infected with hepatitis B (a virus that infects the liver and may cause severe liver damage), but not have any symptoms of the disease. In this case, taking the combination of sofosbuvir and velpatasvir may increase the risk that your infection will become more serious or life-threatening and you will develop symptoms. Tell your doctor if you have or ever had a hepatitis B virus infection. Your doctor will order a blood test to see if you have or have ever had hepatitis B infection. Your doctor will also monitor you for signs of hepatitis B infection during and for several months after your treatment. If necessary, your doctor may give you medication to treat this infection before and during your treatment with the combination of sofosbuvir and velpatasvir. If you experience any of the following symptoms during or after your treatment, call your doctor immediately: excessive tiredness, yellowing of the skin or eyes, loss of appetite, nausea or vomiting, pale stools, stomach pain, or dark urine. Keep all appointments with your doctor and the laboratory. Your doctor may order certain tests before, during, and after your treatment to check your body's response to the combination of sofosbuvir and velpatasvir. Talk to your doctor about the risk(s) of taking the combination of sofosbuvir and velpatasvir.
Before taking sofosbuvir and velpatasvir,
- tell your doctor and pharmacist if you are allergic to sofosbuvir, velpatasvir, any other medications, or any of the ingredients in sofosbuvir and velpatasvir tablets. Ask your pharmacist for a list of the ingredients.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements you are taking or plan to take. Be sure to mention any of the following: amiodarone (Nexterone, Pacerone); atorvastatin (Lipitor, in Caduet); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); digoxin (Lanoxin); efavirenz (Sustiva, in Atripla); oxcarbazepine (Oxtellar, Trileptal); phenobarbital; phenytoin (Dilantin, Phenytek); proton-pump inhibitors such as dexlansoprazole (Dexilant), esomeprazole (Nexium, in Vimovo), lansoprazole (Prevacid, in Prevpac), omeprazole (Prilosec, Zegerid), pantoprazole (Protonix), and rabeprazole (AcipHex): rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, in Rifamate, Rifater); rifapentine (Priftin); rosuvastatin (Crestor); tenofovir DF (Viread, in Atripla, Complera, Stribild, Truvada, others); tipranavir (Aptivus) when taken with ritonavir (Norvir); topotecan (Hycamtin); and warfarin (Coumadin, Jantoven). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with sofosbuvir and velpatasvir, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
- if you are taking antacids, take them 4 hours before or 4 hours after sofosbuvir and velpatasvir.
- tell your doctor if you are taking a medication for indigestion, heartburn, or ulcers (H2 blockers) such as cimetidine, ranitidine (Zantac), famotidine (Pepcid, in Duexis), or nizatidine. Your doctor may tell you to take this medication 12 hours before or 12 hours after sofosbuvir and velpatasvir, or at the same time that you take sofosbuvir and velpatasvir.
- tell your doctor what herbal products you are taking, especially St. John's wort.
- tell your doctor if you have human immunodeficiency virus (HIV), or have or have ever had any type of liver problem other than hepatitis C or kidney disease or are on dialysis.
- tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking sofosbuvir and velpatasvir, call your doctor.
- lack of energy
- feeling irritable
- feeling depressed