Demerol (Meperidine)

Sorry, we do not offer this product as it is a controlled/narcotic medication.


To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more


Meperidine Information

(me per' i deen)

Meperidine injection may cause serious or life-threatening breathing problems, especially during the first 24 to 72 hours of your treatment and any time your dose is increased. Your doctor will monitor you carefully during your treatment. Tell your doctor if you have or have ever had slowed breathing or asthma. Your doctor will probably tell you not to use meperidine injection. Also tell your doctor if you have or have ever had lung disease such as chronic obstructive pulmonary disease (COPD; a group of diseases that affect the lungs and airways), a head injury, or any condition that increases the amount of pressure in your brain. The risk that you will develop breathing problems may be higher if you are an older adult or are weak or malnourished due to disease. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment: slowed breathing, long pauses between breaths, or shortness of breath. Taking certain medications during your treatment with meperidine injection may increase the risk that you will experience breathing problems or other serious, life threatening breathing problems, sedation, or coma. Tell your doctor if you are taking or plan to take any of the following medications: benzodiazepines such as alprazolam (Xanax), diazepam (Diastat, Valium), estazolam, flurazepam, lorazepam (Ativan), and triazolam (Halcion); medications for anxiety, nausea, or pain; muscle relaxants; sedatives; sleeping pills; or tranquilizers. Your doctor may need to change the dosages of your medications and will monitor you carefully. If you use meperidine injection with any of these medications and you develop any of the following symptoms, call your doctor immediately or seek emergency medical care: unusual dizziness, lightheadedness, extreme sleepiness, slowed or difficult breathing, or unresponsiveness. Be sure that your caregiver or family members know which symptoms may be serious so they can call the doctor or emergency medical care if you are unable to seek treatment on your own. Drinking alcohol, taking prescription or nonprescription medications that contain alcohol, or using street drugs during your treatment with meperidine increases the risk that you will experience serious, life-threatening side effects. Do not drink alcohol, take prescription or nonprescription medications that contain alcohol, or use street drugs during your treatment. Meperidine injection may be habit-forming. Do not use more of it, use it more often, or use it in a different way than directed by your doctor. Tell your doctor if you or anyone in your family drinks or has ever drunk large amounts of alcohol, uses or has ever used street drugs, or has overused prescription medications, if you need to take narcotic pain medications regularly in order to feel well. or if you have or have ever had depression or another mental illness. There is a greater risk that you will overuse meperidine if you have or have ever had any of these conditions. Do not allow anyone else to use your medication. Meperidine injection may harm or cause death to other people who use your medication, especially children. Tell your doctor if you are pregnant or plan to become pregnant. If you using meperidine injection regularly during your pregnancy, your baby may experience life-threatening withdrawal symptoms after birth. Tell your baby's doctor right away if your baby experiences any of the following symptoms: irritability, hyperactivity, abnormal sleep, high-pitched cry, uncontrollable shaking of a part of the body, vomiting, diarrhea, or failure to gain weight. Talk to your doctor about the risks of using meperidine injection.
Meperidine injection is used to relieve moderate to severe pain. It may also be used before and during surgery or other medical procedures. Meperidine injection is in a class of medications called opiate (narcotic) analgesics. It works by changing the way the body senses pain.
Meperidine injection comes as a solution (liquid) to inject subcutaneously (just under the skin), intramuscularly (into a muscle), or intravenously (into a vein). It is usually injected subcutaneously or intramuscularly once every 3 to 4 hours as needed. Use meperidine injection exactly as directed. Your doctor may adjust your dose of meperidine injection during your treatment, depending on how well your pain is controlled and on the side effects that you experience. Talk to your doctor about how you are feeling during your treatment with meperidine injection. If you have used meperidine injection for longer than a few days, do not stop using it suddenly. If you suddenly stop using meperidine injection, you may experience withdrawal symptoms including restlessness; teary eyes; runny nose; yawning; sweating; chills; muscle, back or joint pain; widening of the pupils; irritability; anxiety; weakness; stomach cramps; difficulty falling asleep or staying asleep; nausea; loss of appetite; vomiting; diarrhea; fast breathing; or fast heartbeat. Your doctor will probably decrease your dose gradually.
    Before using meperidine injection
  • tell your doctor and pharmacist if you are allergic to meperidine, any other medications, or ingredients in meperidine injection. Ask your pharmacist for a list of the ingredients.
  • do not use meperidine injection if you are taking a monoamine oxidase (MAO) inhibitor such as isocarboxazid (Marplan), linezolid (Zyvox), methylene blue, phenelzine (Nardil), procarbazine (Matulane), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) or if you have stopped taking any of these medications within the past 2 weeks. Your doctor will probably tell you not to use meperidine injection if you are taking one or more of these medications.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: cyclobenzaprine (Amrix); dextromethorphan (found in many cough medications; in Nuedexta); lithium (Lithobid, in Librax); medications for migraine headaches such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex, in Treximet), and zolmitriptan (Zomig); mirtazapine (Remeron); 5HT3 serotonin blockers such as alosetron (Lotronex), dolasetron (Anzemet), granisetron (Kytril), ondansetron (Zofran, Zuplenz), or palonosetron (Aloxi); selective serotonin-reuptake inhibitors such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, in Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Prozac, Pexeva), and sertraline (Zoloft); serotonin and norepinephrine reuptake inhibitors such as duloxetine (Cymbalta), desvenlafaxine (Khedezla, Pristiq), milnacipran (Savella), and venlafaxine (Effexor); tramadol (Conzip, Ultram); trazodone (Oleptro); or tricyclic antidepressants ('mood elevators') such as amitriptyline, clomipramine (Anafranil), desipramine (Norpramin), doxepin (Silenor), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil). Many other medications may also interact with meperidine, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Also tell your doctor or pharmacist if you are taking narcotic medications for pain or if you have recently taken these medications. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor what herbal products you are taking, especially St. John's wort and tryptophan.
  • tell your doctor if you have or have ever had problems urinating; Addison's disease (a condition in which the body does not produce certain important chemicals); prostatic hypertrophy (enlargement of a male reproductive gland called the prostate); urethral stricture (narrowing of the opening through which urine leaves the body); seizures; or thyroid, heart, kidney, or liver disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while using meperidine injection, call your doctor.
  • you should know that this medication may decrease fertility in men and women. Talk to your doctor about the risks of using meperidine.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are using meperidine injection.
  • you should know that meperidine may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
  • you should know that meperidine may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.
Unless your doctor tells you otherwise, continue your normal diet.
Meperidine injection may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
  • lightheadedness
  • headache
  • agitation
  • constipation
  • uncontrollable shaking of a part of your body
  • blurred vision
  • dry mouth
  • pain or redness at injection site
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:
  • slowed breathing
  • agitation, hallucinations (seeing things or hearing voices that do not exist), fever, sweating, confusion, fast heartbeat, shivering, severe muscle stiffness or twitching, loss of coordination, nausea, vomiting, or diarrhea
  • nausea, vomiting, loss of appetite, weakness, or dizziness
  • inability to get or keep an erection
  • decreased sexual desire
  • irregular menstruation
  • intense happiness
  • sad mood
  • rash
  • itching
  • flushing
  • hives
  • seizures
  • hallucinations
Meperidine injection may cause other side effects. Call your doctor if you have any unusual problems while using this medication.
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.
Keep all appointments with your doctor. Your doctor may order certain lab tests to check your body's response to meperidine. Before having any laboratory test (especially those that involve methylene blue), tell your doctor and the laboratory personnel that you are using meperidine. This prescription is not refillable. If you continue to have pain after you finish meperidine, call your doctor. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.