Combivir (Zidovudine / Lamivudine)
(℞) Prescription required. May be split. Product of Canada. Shipped from Canada.
Generic equivalents for Combivir... What are generics?
Zidovudine / Lamivudine (℞)
(℞) Prescription required. Product of Canada. Shipped from Canada.
To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more
Zidovudine / Lamivudine Information
(la mi' vyoo deen) (zye doe' vyoo deen)Lamivudine and zidovudine may decrease the number of certain cells in your blood, including red and white blood cells. Tell your doctor if you have or have ever had a low number of any type of blood cells or any blood disorders such as anemia (a lower than normal number of red blood cells) or bone marrow problems. If you experience any of the following symptoms, call your doctor immediately: unusual bleeding or bruising; shortness of breath; pale skin; fever, sore throat, chills, and other signs of infection; or unusual tiredness or weakness. Lamivudine and zidovudine may cause muscle disorders, especially when used for a long period of time. Tell your doctor if you have or have ever had any disease of the muscles or muscle weakness. If you experience muscle pain or muscle weakness, call your doctor immediately. Lamivudine and zidovudine may cause life-threatening damage to the liver and a potentially life-threatening condition called lactic acidosis (buildup of lactic acid in the blood). Tell your doctor if you have or have ever had liver disease. If you have liver disease your doctor will probably tell you not to take lamivudine and zidovudine. If you experience any of the following symptoms, call your doctor immediately or get emergency medical treatment: nausea, vomiting, pain in the upper right part of your stomach, loss of appetite, extreme tiredness, unusual bleeding or bruising, weakness, dizziness, lightheadedness, fast or irregular heartbeat, trouble breathing, dark yellow or brown urine, light-colored bowel movements, yellowing of the skin or eyes, feeling cold, especially in the arms or legs, or muscle pain that is different than any muscle pain you usually experience. Tell your doctor if you have or think you may have hepatitis B virus infection (HBV; an ongoing liver infection). Your doctor may test you to see if you have HBV before you begin your treatment with lamivudine and zidovudine. If you have HBV and you take lamivudine and zidovudine, your condition may suddenly worsen when you stop taking lamivudine and zidovudine. Your doctor will examine you and order lab tests regularly for several months after you stop taking lamivudine to see if your HBV has worsened. Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests during and after your treatment to check your body's response to lamivudine and zidovudine.
Before taking lamivudine and zidovudine,
- tell your doctor or pharmacist if you are allergic to lamivudine (Epivir, Epivir HBV, others); zidovudine (Retrovir); any other medications; or any of the ingredients in lamivudine and zidovudine tablets. Ask your pharmacist for a list of the ingredients.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements and herbal products you are taking. Be sure to mention any of the following: atovaquone (Malarone, Mepron), certain medications for cancer such as doxorubicin (Doxil), fluconazole (Diflucan), ganciclovir (Cytovene, Valcyte), interferon alpha, ,methadone (Dolophine, Methadose), ribavirin (Copegus, Rebetrol, others), rifampin (Rifadin, Rimactane, in Rifamate, in Rifater), and stavudine (Zerit). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with lamivudine and zidovudine, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
- in addition to the conditions listed in the IMPORTANT WARNING section, tell your doctor if you have or have ever had pancreatitis (swelling of the pancreas that does not go away) or kidney disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking lamivudine and zidovudine, call your doctor. You should not breastfeed if you are infected with HIV or if you are taking lamivudine and zidovudine.
- you should be aware that your body fat may increase or move to different areas of your body, such as your upper back, neck (''buffalo hump''), breasts, and around your stomach. You may notice a loss of body fat from your face, legs, and arms.
- you should know that while you are taking medications to treat HIV infection, your immune system may get stronger and begin to fight other infections that were already in your body. This may cause you to develop symptoms of those infections. If you have new or worsening symptoms at any time during your treatment with lamivudine and zidovudine, be sure to tell your doctor.
- difficulty falling asleep or staying asleep
- stuffy nose
- joint pain
- difficulty breathing or swallowing
- numbness, tingling, or burning in your fingers or toes