Wellbutrin XL Price - Get 80% Off (Comparison Guide)

Living with Depression: The Hidden Struggle

Wellbutrin XL (Bupropion Hydrochloride Extended-Release) is a prescription medication used to treat major depressive disorder (MDD) and seasonal affective disorder (SAD). It may also be prescribed off-label for smoking cessation and ADHD. Wellbutrin XL is an extended-release formulation taken once daily, offering all-day symptom control with a single dose.

While clinically effective, Wellbutrin XL (Bupropion Hydrochloride) can be prohibitively expensive in the U.S. without insurance. However, there are cost-saving strategies—particularly through international online pharmacies—that can reduce your monthly out-of-pocket expense by over 90%.

Key Takeaways

  • CIPA-Certified Online Pharmacies Offer Major Discounts: Certified international pharmacies like DrugMart and Planet Drugs Direct offer Wellbutrin XL 300mg for as little as $220.17 for a 90-day supply, or about $73.39 per month—representing savings of over 90% compared to U.S. retail pharmacies. Purchase from DrugMart.

  • Retail Pharmacies Charge Over $2,600 Monthly Without Insurance: U.S. pharmacies such as Amazon Pharmacy, Walgreens, and CVS charge $2,585 to over $2,685 for a 30-day supply of Wellbutrin XL 300mg when paying cash.

  • Wellbutrin XL Is Covered by Most Medicare Part D Plans: However, out-of-pocket costs still vary, especially in the deductible and coverage gap phases. Beneficiaries may pay anywhere from $40 to $150+ per month.

Cheapest Online Pharmacies for Wellbutrin XL (Bupropion 300mg)

Below are the lowest available prices from verified online pharmacies for a 90-tablet supply (300mg), typically lasting 3 months at one tablet daily.

Pharmacy

Prescription Required

Price (Estimated)

Dosage

Tablets

Website

DrugMart

Yes

$220.17

300mg

90

Visit

Planet Drugs Direct

Yes

$220.17

300mg

90

Visit

Amazon Pharmacy

Yes

$2,955.80

300mg

30

Visit

Prices as of June 2nd, 2025. Pricing may change based on prescription, quantity, and location.

U.S. Retail Prices for Wellbutrin XL (Bupropion 300mg)

Retail prices for Wellbutrin XL (Bupropion Hydrochloride) remain extremely high in the U.S. Here’s what you can expect to pay at major pharmacy chains for a 30-day supply:

Pharmacy

Retail Price

Meijer Pharmacy

$2,666.00

Mariano’s

$2,666.00

Capsule Pharmacy

$2,613.00

Aurora Pharmacy

$2,666.00

CVS Pharmacy

$2,585.00

Target (CVS)

$2,666.00

Jewel-Osco

$2,424.00

Walgreens

$2,634.00

Walgreens Specialty Pharmacy

$2,666.00

Walmart

$2,397.00

Walmart Neighborhood Market

$2,397.00

Costco

$2,685.00

Other Pharmacies

$2,455.00

 Prices reflect 30 tablets of 300mg Wellbutrin XL. Cost may vary by location and stock.

How to Save on Wellbutrin XL (Bupropion Extended-Release)

Here’s how to save on Wellbutrin XL (Bupropion Hydrochloride):

1. Use Medicare Part D Coverage

Wellbutrin XL (Bupropion Hydrochloride) is covered under most Medicare Part D plans. However, pricing depends on your plan’s tier placement and coverage phase. In the deductible or “donut hole” stage, monthly costs can rise significantly. Use the Medicare Plan Finder to estimate your monthly cost based on your pharmacy and region.

2. Ask About Manufacturer Assistance

The manufacturer of Wellbutrin XL (Bupropion Hydrochloride), Bausch Health, may offer patient assistance programs for individuals with financial hardship or those on commercial insurance. These programs typically do not apply to Medicare or Medicaid recipients.

To learn more about Wellbutrin’s assistance program, visit this website.

3. Use CIPA-Certified Online Pharmacies

Patients without insurance or facing high copays may benefit from international pharmacy alternatives. Trusted CIPA-certified pharmacies like DrugMart and Planet Drugs Direct offer prices more than 90% lower than U.S. chains and ship directly to U.S. addresses with a valid prescription.

Common Questions

Common questions and answers about Wellbutrin XL (Bupropion Hydrochloride):

1. Is Wellbutrin XL covered by Medicare?

Yes, Wellbutrin XL (bupropion extended-release) is typically covered by Medicare Part D plans, though several factors may influence your out-of-pocket costs:

  • Coverage: Most Part D plans include bupropion XL on their formularies.

  • Tier Placement: It’s usually listed as a Tier 2 medication—meaning it is moderately priced, but your copay will likely be higher than Tier 1 (generic) drugs.

  • Quantity Limits: Some plans may restrict how much you can fill at once (e.g., 30-day supply only), and prior authorization may be required from your doctor to override limits or confirm medical necessity.

  • Cost: Your monthly copay will depend on your plan and where you are in the coverage cycle—deductible, initial coverage, coverage gap, or catastrophic coverage.

  • Savings Tips:

    • Ask your doctor to prescribe a 90-day supply if your plan allows—it may reduce your total cost.

    • Look into prescription discount coupons that can be used alongside your Medicare plan (though some plans may restrict coupon use).

    • Talk to your provider about potential lower-cost alternatives if coverage or copays are prohibitive.

To determine your exact cost:

  • Check your plan’s formulary (drug list) on the insurance provider’s website or printed documents.

  • Call your plan’s customer service to verify tier placement, prior authorization requirements, and out-of-pocket estimates.

  • Consult with your doctor or pharmacist to explore the most cost-effective options for your treatment plan.

2. How much does Wellbutrin XL cost with Medicare?

Costs generally range from $40 to $150 per month, depending on your plan and whether you are in the deductible or coverage gap phase.

3. What’s the best way to save if I don’t have insurance?

Ordering from a CIPA-certified international pharmacy can lower your cost from nearly $2,600/month to just $73/month, saving you over $30,000 annually.

Take Control of Rising Prescription Drug Costs With Drugmart.com Drugmart.com is the Canadian online prescription referral service that you can trust to help you tackle the high price of prescription drugs. We bring you savings right to your door. Shop now for prescription medication to begin saving on rising drug prices.


Sources

  1. Basuch Health. (n.d.). Wellbutrin XL savings & access. Retrieved June 2, 2025, from https://www.wellbutrinxl.com/savings-access/

  2. U.S. Food and Drug Administration. (2017). Wellbutrin XL (bupropion hydrochloride extended-release tablets) [Labeling] (NDAs 018644/S-052). Retrieved June 2, 2025, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/018644s052lbl.pdf


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The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.